Conventional coalbed methane (CBM) reservoir models for injection fall-off testing often disregard the quadratic pressure gradient's impact. This omission leads to discrepancies in simulating the transient behavior of formation fluids and extracting critical reservoir properties. Accurate determination of permeability, storability, and other properties is crucial for effective reservoir characterization and production forecasting. Inaccurate estimations can lead to suboptimal well placement, ineffective production strategies, and ultimately, missed economic opportunities. To address this shortcoming, we present a novel analytical model that explicitly incorporates the complexities of the quadratic pressure gradient and dual-permeability flow mechanisms, prevalent in many CBM formations where nanopores are rich, presenting a kind of natural nanomaterial. This model offers significant advantages over traditional approaches. By leveraging variable substitution, it facilitates the derivation of analytical solutions in the Laplace domain, subsequently converted to real-space solutions for practical application. These solutions empower reservoir engineers to generate novel type curves, a valuable tool for analyzing wellbore pressure responses during injection fall-off tests. By identifying distinct flow regimes within the reservoir based on these type curves, engineers gain valuable insights into the dynamic behavior of formation fluids. This model goes beyond traditional approaches by investigating the influence of the quadratic pressure gradient coefficient, inter-porosity flow coefficient, and storability ratio on the pressure response. A quantitative comparison with traditional models further elucidates the key discrepancies caused by neglecting the quadratic pressure gradient. The results demonstrate the proposed model's ability to accurately depict the non-linear flow behavior observed in CBM wells. This translates to more reliable pressure and pressure derivative curves that account for the impact of the quadratic pressure gradient.
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http://dx.doi.org/10.3390/nano14131070 | DOI Listing |
PLoS One
January 2025
Department of Statistics and Probability, Michigan State University, East Lansing, MI, United States of America.
The genetic basis of complex traits involves the function of many genes with small effects as well as complex gene-gene and gene-environment interactions. As one of the major players in complex diseases, the role of gene-environment interactions has been increasingly recognized. Motivated by epidemiology studies to evaluate the joint effect of environmental mixtures, we developed a functional varying-index coefficient model (FVICM) to assess the combined effect of environmental mixtures and their interactions with genes, under a longitudinal design with quantitative traits.
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January 2025
Division of Mechanical and Biomedical Engineering, Ewha Womans University, Seoul, 03760, Republic of Korea.
This contribution details a new high-fidelity finite element analysis (FEA) methodology for the investigation of the effect of the graft size on the pressure distribution developing at the calcaneocuboid joint after the Evans osteotomy procedure. The FEA model includes all 28 bones of the foot up to the distal end of fibula and tibia as well as soft tissues, tendons, and muscles. The developed FEA model was validated by comparing the in-vivo pressure distribution on the foot plantar with the in-silico results, resulting in a low deviation equal to 7.
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January 2025
Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education, School of Energy and Power Engineering, Dalian University of Technology, Dalian 116023, P. R. China.
Interfacial tension () between CO and brine depends on chemical components in multiphase systems, intricately evolving with a change in temperature. In this study, we developed a convolutional neural network with a multibranch structure (MBCNN), which, in combination with a compiled data set containing measurement data of 1716 samples from 13 available literature sources at wide temperature and pressure ranges (273.15-473.
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January 2025
Department of Neurosurgery, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan.
Background: Cerebral autoregulation is a robust regulatory mechanism that stabilizes cerebral blood flow in response to reduced blood pressure, thereby preventing cerebral ischaemia. Scientists have long believed that cerebral autoregulation also stabilizes cerebral blood flow against increases in intracranial pressure, which is another component that determines cerebral perfusion pressure. However, this idea was inconsistent with the complex pathogenesis of normal pressure hydrocephalus, which includes components of chronic cerebral ischaemia due to mild increases in intracranial pressure.
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January 2025
Hunan Provincial Key Laboratory of Geotechnical Engineering for Stability Control and Health Monitoring, Hunan University of Science and Technology, Xiangtan, 411201, People's Republic of China.
The accumulation and discharge amount of coal gangue are substantial, occupying significant land resources over time. Utilizing coal gangue as subgrade filler can generate notable economic and social benefits. Coal gangue coarse-grained soil (CGSF) was used to conduct a series of large-scale vibration compaction tests and large-scale triaxial tests.
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