As a new type of high-performance material, gradient structural steel is widely used in engineering fields due to its unique microstructure and excellent mechanical properties. For the prevalent fatigue failure problem, the rate of change in the local grain size gradients along the structure (referred to as the gradient rate) is a key parameter in the design of gradient structures, which significantly affects the fatigue performance of gradient structural steel. In this study, a new method of 'Voronoi primary + secondary modeling' is adopted to successfully establish three typical high-strength steel models corresponding to the convex-, linear-, and concave-type gradient rates for gradient structures, focusing on the stress-strain response and crack propagation in structural steel with different gradient rates under cyclic loading. It was found that the concave gradient rate structural model is dominated by finer grains with larger volume fraction, which is conducive to hindering fatigue crack propagation and has the longest fatigue life, which is 16.16% longer than that of the linear gradient rate structure and 23.66% longer than that of the convex gradient rate structure. The simulation results in this study are consistent with the relevant experimental phenomena. Therefore, when regulating the gradient rate, priority should be given to increasing the volume fraction of fine grains and designing a gradient rate structure dominated by fine grains to improve the fatigue life of the material. This study presents a new strategy for designing engineering materials with better service performance.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11242507 | PMC |
http://dx.doi.org/10.3390/ma17133210 | DOI Listing |
PLoS One
January 2025
CFD Research Corporation, Huntsville, AL, United States of America.
Purpose: To assess physiological metrics during the use of a commercially available bilateral active ankle exoskeleton during a challenging military-relevant task and if use of the exoskeleton during this task influences: metabolic load, physiological measures or rate of perceived exertion.
Methods: Nine healthy volunteers (5M, 4F) completed this randomized cross-over design trial, with a baseline visit and two randomized test sessions (with/without the exoskeleton). Variables included impact on time to exhaustion during walking on a treadmill at varying speeds and gradients (0-15%) at 26.
J Imaging
January 2025
Istituto di Scienze Applicate e Sistemi Intelligenti (ISASI), Consiglio Nazionale delle Ricerche (CNR), DHITECH, Campus Università del Salento, Via Monteroni s.n., 73100 Lecce, Italy.
Despite significant advancements in the automatic classification of skin lesions using artificial intelligence (AI) algorithms, skepticism among physicians persists. This reluctance is primarily due to the lack of transparency and explainability inherent in these models, which hinders their widespread acceptance in clinical settings. The primary objective of this study is to develop a highly accurate AI-based algorithm for skin lesion classification that also provides visual explanations to foster trust and confidence in these novel diagnostic tools.
View Article and Find Full Text PDFMembranes (Basel)
December 2024
Sonyo Refrigeration (Dalian) Co., Ltd., Dalian 116699, China.
The absorption refrigeration system (ARS) stands as a remarkable device that is capable of efficiently harnessing low-grade thermal energy and converting it into cooling capacity. The reverse electrodialysis (RED) system harvests the salinity gradient energy embedded in two solutions of different concentrations into electricity. An innovative RED-ARS integration system is proposed that outputs cooling capacity and electric energy, driven by waste heat.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
Institute for Advanced Research, Cixi Biomedical Research Institute, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
The acidic tumor microenvironment, a hallmark of many solid tumors, is primarily induced by the high glycolytic rate of tumor cells. To avoid acidosis, tumor cells ingeniously maintain an acidic extracellular pH while keeping a relatively alkaline intracellular pH. Overturning the unique pH gradient of tumor cells has exhibited to be a viable approach for cancer therapy.
View Article and Find Full Text PDFBull Math Biol
January 2025
Section of Epidemiology, University of Copenhagen, Copenhagen, Denmark.
Using genetic data to infer evolutionary distances between molecular sequence pairs based on a Markov substitution model is a common procedure in phylogenetics, in particular for selecting a good starting tree to improve upon. Many evolutionary patterns can be accurately modelled using substitution models that are available in closed form, including the popular general time reversible model (GTR) for DNA data. For more complex biological phenomena, such as variations in lineage-specific evolutionary rates over time (heterotachy), other approaches such as the GTR with rate variation (GTR ) are required, but do not admit analytical solutions and do not automatically allow for likelihood calculations crucial for Bayesian analysis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!