Background: Fear of falling (FOF) has emerged as a significant public health issue, contributing to excess disability among middle-aged and older adults. The association between FOF and mortality remains unclear.
Methods: Prominent electronic databases (PubMed, Web of Science, the Cochrane Library, Embase, CINHAL, PsycINFO, Scopus, China National Knowledge Infrastructure, China Biology Medicine disc, and Wanfang Database) were searched from inception until October 21, 2023 (data updated on June 9, 2024), for cohort or longitudinal studies investigating the association between FOF and mortality. The heterogeneity between studies was quantitatively assessed using I. A fixed-effect model calculated the pooled effect size.
Results: A total of seven cohort studies, including 27,714 participants, were analyzed in this systematic review and meta-analysis. The meta-analysis results demonstrated a positive association between FOF and mortality, with a significant increase in the risk of mortality for those with FOF (hazard ratio [HR]:1.29, 95 % confidence interval [CI]: 1.19-1.41, p < 0.05). Subgroup analysis indicated that age, male sex, clinical diagnosis of depression, number of chronic diseases, activity restriction due to FOF, and FOF levels were associated with mortality.
Conclusions: FOF and mortality have a positive association, which needs to be confirmed by further prospective studies with large samples and long-term follow-up to provide evidence for clinicians to intervene in FOF to reduce mortality in middle-aged and older adults.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.gerinurse.2024.06.032 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Common Physical Performance Tests for Evaluating Health in Older Adults: Cross-Sectional Study.
Interact J Med Res
November 2024
Disability, Aging and Technology Cluster, University of Central Florida, Orlando, FL, United States.
Article Synopsis
- Interdisciplinary evaluation of older adults' health care is crucial for preventing chronic conditions, but it's unclear which physical performance tests (PPTs) are the best for assessing their health status.
- This study aimed to analyze how overall physical capacity and factors like fear of falling affect the results of three common tests: the Short Physical Performance Battery (SPPB), 6-minute walk test (6MWT), and Incremental Shuttle Walk Test (ISWT).
- Results showed that the SPPB offered the most comprehensive insights, with significant links to physical activity levels and fear of falling, while the ISWT also showed similar predictive factors but with slightly lower effectiveness.
Association between fear of falling and mortality in middle-aged and older adults: A systematic review and meta-analysis.
Geriatr Nurs
October 2024
Dean Office, Sichuan Nursing Vocational College, Chengdu, China. Electronic address:
Background: Fear of falling (FOF) has emerged as a significant public health issue, contributing to excess disability among middle-aged and older adults. The association between FOF and mortality remains unclear.
Methods: Prominent electronic databases (PubMed, Web of Science, the Cochrane Library, Embase, CINHAL, PsycINFO, Scopus, China National Knowledge Infrastructure, China Biology Medicine disc, and Wanfang Database) were searched from inception until October 21, 2023 (data updated on June 9, 2024), for cohort or longitudinal studies investigating the association between FOF and mortality.
Assessing the Effects of Curcumin and 450 nm Photodynamic Therapy on Oxidative Metabolism and Cell Cycle in Head and Neck Squamous Cell Carcinoma: An In Vitro Study.
Cancers (Basel)
April 2024
BIO-Photonics Overarching Research Laboratory (BIOPHOR), Department of Earth, Environmental and Life Sciences (DISTAV), University of Genoa, 16132 Genoa, Italy.
Oral cancer is the 16th most common malignant tumor worldwide. The risk of recurrence and mortality is high, and the survival rate is low over the following five years. Recent studies have shown that curcumin causes apoptosis in tumor cells by affecting FF-ATP synthase (ATP synthase) activity, which, in turn, hinders cell energy production, leading to a loss of cell viability.
View Article and Find Full Text PDFTridirectional association between probable depression, fear of falling and falls among middle-aged and older adults in Thailand.
Arch Gerontol Geriatr
June 2023
Department of Health Education and Behavioral Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand; Department of Psychology, University of the Free State, Bloemfontein, South Africa; Department of Psychology, College of Medical and Health Science, Asia University, Taichung, Taiwan. Electronic address:
Purpose: Depression is a major issue in the aging population, which may be related to fear of falling (FOF) and falls contributing to increased morbidity and mortality. The aim of the study was to assess the tridirectional associations between probable depression (PD), FOF and falls in a longitudinal study in Thailand.
Methods: Longitudinal data of participants (≥45 years; N = 3708) from two consecutive waves (in 2015 and 2017) of the Health, Aging and Retirement in Thailand (HART) study were analysed.
What contributes most to the SPPB and its subscores in hospitalized geriatric patients: an ICF model-based approach.
BMC Geriatr
August 2022
Department of Neurology, University Hospital Schleswig-Holstein, Arnold-Heller-Straße 3, 24105, Kiel, Germany.
Background: Mobility deficits are highly prevalent among geriatric patients and have serious impact on quality of life, hospitalizations, and mortality. This study aims to capture predictors of mobility deficits in hospitalized geriatric patients using the International Classification of Functioning, Disability and Health (ICF) model as a framework.
Methods: Data were obtained from n = 397 patients (78 ± 7 years, 15 ± 7 ICD-11 diagnoses) on a geriatric ward at time of admission.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!