One of the primary challenges in ring single-element photoacoustic tomography systems is the low image quality in areas away from the center of the ring. This is mainly due to the limited field of view (FOV) of each transducer, which in turn reduces the imaging FOV. To address this shortcoming, we have put forward a practical and straightforward solution to enhance the FOV of circular scanning-based photoacoustic tomography (CS-PAT). This is accomplished by placing transducers at different angles instead of using a single transducer placed at a normal angle to the imaging target. We also modified the ring scanner inner wall surface to significantly reduce photoacoustic reverberation. By imaging several phantoms, we show a significant improvement in the images generated by our system imaging from 4.1 to over 7 for the signal-to-noise ratio and structural similarity index increased from 41% to 70%.
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http://dx.doi.org/10.1002/jbio.202400125 | DOI Listing |
Photoacoustics
February 2025
Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States.
Pattern recognition analysis in brain research has improved understanding of sensory processing and led to the identification of default brain networks in neuroimaging studies. The current study uses pattern recognition analysis to extend our previous findings showing conditioned fear learning and novelty-exposure (i.e.
View Article and Find Full Text PDFPhotoacoustics
February 2025
NYU Langone Health, Tech4Health and Neuroscience Institutes, and Department of Ophthalmology, New York City, USA.
Measuring whole-brain distributed functional activity is an important unmet need in neuroscience, requiring high temporal resolution and cellular specificity across large volumes. Functional optoacoustic neuro-tomography (FONT) with genetically encoded calcium ion indicators is a promising approach towards this goal. However, it has not yet been applied in the near-infrared (NIR) range that provides deep penetration and low vascular background optimal for neuroimaging.
View Article and Find Full Text PDFPhotoacoustics
February 2025
Institute of Fiber Optics, Shanghai University, Shanghai 201800, China.
Photoacoustic imaging (PAI) is an emerging hybrid imaging technology that combines the advantages of optical and ultrasound imaging. Despite its excellent imaging capabilities, PAI still faces numerous challenges in clinical applications, particularly sparse spatial sampling and limited view detection. These limitations often result in severe streak artifacts and blurring when using standard methods to reconstruct images from incomplete data.
View Article and Find Full Text PDFPhys Med Biol
January 2025
North China Electric Power University - Baoding Campus, North China Electric Power University, Baoding, Hebei Province, P.R.China, Baoding, Hebei, 071003, CHINA.
Objective: The optical absorption properties of biological tissues in photoacoustic tomography are typically quantified by inverting acoustic measurements. Conventional approaches to solving the inverse problem of forward optical models often involve iterative optimization. However, these methods are hindered by several challenges, including high computational demands, the need for regularization, and sensitivity to both the accuracy of the forward model and the completeness of the measurement data.
View Article and Find Full Text PDFMicrosurgery
January 2025
Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Thinning of anterolateral thigh flap is challenging. Anatomical studies have shown variations in arterial branching patterns in the subcutaneous layer, which were suspected to be the reason for the high frequency of thinning failures. We attempted to visualize subcutaneous arterial courses preoperatively and perform thinning of perforator flaps using this information appropriately.
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