Necrostatin-1: a promising compound for neurological disorders.

Front Cell Neurosci

Department of Clinical Pharmacy, Xiangtan Central Hospital, Xiangtan, China.

Published: June 2024

Necrostatin-1, a small molecular alkaloid, was identified as an inhibitor of necroptosis in 2005. Investigating the fundamental mechanism of Necrostatin-1 and its role in various diseases is of great significance for scientific and clinical research. Accumulating evidence suggests that Necrostatin-1 plays a crucial role in numerous neurological disorders. This review aims to provide a comprehensive overview of the potential functions of Necrostatin-1 in various neurological disorders, offering valuable insights for future research.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236683PMC
http://dx.doi.org/10.3389/fncel.2024.1408364DOI Listing

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