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Revolutionizing renal research: The future of kidney-on-a-chip in biotechnology. | LitMetric

Revolutionizing renal research: The future of kidney-on-a-chip in biotechnology.

Regen Ther

Department of Clinical Engineering, Faculty of Medical Science and Technology, Gunma Paz University, 3-3-4 Tonyamachi, Takasaki-shi, Gunma, 370-0006, Japan.

Published: June 2024

AI Article Synopsis

Article Abstract

In vitro models of kidneys have limited effectiveness owing to the complex structure and functions of the kidney when compared with other organs. Therefore many renal function evaluations are currently being carried out through animal experiments. In contrast, efforts are being made to apply biomimetic systems, such as organ-on-a-chip, which is based on microfluidic device technology, to serve as an in vitro model for the kidney. These systems aimed to recreate a physiological cultivation environment. This review has provided an overview of organ-on-a-chip research focused on glomeruli and tubules as in vitro models for the kidney and discusses future prospects.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11237358PMC
http://dx.doi.org/10.1016/j.reth.2024.06.006DOI Listing

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