AI Article Synopsis
- Mucinous tubular and spindle cell carcinoma is a rare type of kidney tumor identified as distinct in the 2004 WHO classification, with ongoing studies refining its characteristics.
- A case involved a 52-year-old African male whose tumor was discovered during surgery for severe kidney trauma.
- The tumor shows varying grades of histology, and features like sarcomatoid differentiation can lead to a more aggressive form of the disease.
Article Abstract
Background: Mucinous tubular and spindle cell carcinoma is a rare renal tumor. It has been recognized as a distinct entity in the 2004 World Health Organization tumor classification. Since then, several dozen of these tumor have been reported with additional complementary morphologic characteristics, immunohistochemical profile, and molecular genetic features that have further clarified its clinicopathologic aspects.
Case Presentation: We report the case of a 52-year-old male African patient who was found to have a mucinous tubular and spindle renal cell carcinoma on a nephrectomy specimen for a severe kidney trauma.
Conclusions: This tumor has a histological spectrum ranging from low to high grade, which includes sarcomatoid differentiation that can confer the tumor an aggressive clinical course.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11241911 | PMC |
| http://dx.doi.org/10.1186/s13256-024-04659-0 | DOI Listing |
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