AI Article Synopsis
- The microbiota has a role in influencing antitumor immunity, but its specific effects on omental antitumor immunity are still not fully understood.
- A study by Meza-Perez et al. discovered that Proteobacteria utilize arginine, which enhances the suppressive abilities of Treg cells.
- This increased Treg cell activity inhibits the body's antitumor immune responses and consequently promotes tumor growth in the omentum.
Article Abstract
The microbiota can impact antitumor immunity, but whether the microbiota regulates omental antitumor immunity remains elusive. In this issue of Cell Host & Microbe, Meza-Perez et al. demonstrated that Proteobacteria consume arginine to increase Treg cell suppressive capacity and inhibit antitumor immune responses, promoting tumor growth in the omentum.
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| http://dx.doi.org/10.1016/j.chom.2024.05.020 | DOI Listing |
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