AI Article Synopsis

  • Cinnamomi ramulus (CR) is a traditional Chinese medicine mainly used for treating wind-cold diseases, but its chemical profile is not fully understood.
  • This study utilized a method combining 75% ethanol extraction and UPLC-Q-Orbitrap-MS to analyze the chemical components of CR, resulting in the identification of 61 different compounds.
  • The identified compounds include various types like phenylpropanoids, coumarins, flavonoids, and more, helping to enhance understanding of CR's chemical makeup and providing a foundation for future research.

Article Abstract

Cinnamomi ramulus (CR) is a common Chinese herbal medicine with a long history. It is often used to treat exogenous wind-cold diseases in clinic, but its chemical compositions remain to be studied. In this study, CR was extracted with 75% ethanol, and UPLC-Q-Orbitrap-MS combined with data post-processing method was used to identify the chemical components in the extract. Through this technology, the components in CR can be separated and accurately identified. A total of 61 compounds were identified, including 14 simple phenylpropanoids, 3 coumarins, 5 lignans, 14 flavonoids, 10 benzoic acids, 8 organic acids, and 7 others. This study confirmed the existence of these compounds in CR and speculated the cleavage pathways of each compound, which enriched the mass spectrometry data and cleavage rules. This study can provide a reference for CR and other research.

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http://dx.doi.org/10.1002/jms.5069DOI Listing

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