Longitudinally extensive transverse myelitis is a rare neurological manifestation caused by dengue infection. Here, we describe the uncommon presentation of a 24-year-old male with fever and maculopapular rash followed by flaccid quadriparesis with acute urinary retention. Magnetic resonance imaging of the whole spine with contrast revealed a long-segment ill-defined hyperintense signal noted in the cord. The patient was managed conservatively with intravenous steroids and later intravenous immunoglobulins. The patient is on regular follow-up and doing well. Currently, the patient is on tablet prednisolone with a tapering dose.
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http://dx.doi.org/10.7759/cureus.62033 | DOI Listing |
Clin Park Relat Disord
December 2024
Boston University, School of Public Health, Boston, MA, USA.
Objective: To determine the role of obesity in the development of Parkinson's disease (PD).
Background: Obesity has been reported to be both a risk factor for PD, as well as potentially protective. The Framingham Heart Study (FHS) is a multigenerational longitudinal cohort study that was started in 1948, which is well-known for its cardiovascular health studies.
Eur J Epidemiol
January 2025
Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.
The Stockholm Early Detection of Cancer Study (STEADY-CAN) cohort was established to investigate strategies for early cancer detection in a population-based context within Stockholm County, the capital region of Sweden. Utilising real-world data to explore cancer-related healthcare patterns and outcomes, the cohort links extensive clinical and laboratory data from both inpatient and outpatient care in the region. The dataset includes demographic information, detailed diagnostic codes, laboratory results, prescribed medications, and healthcare utilisation data.
View Article and Find Full Text PDFSci Rep
January 2025
Division of Cardiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Myocyte disarray and fibrosis are underlying pathologies of hypertrophic cardiomyopathy (HCM) caused by genetic mutations. However, the extent of their contributions has not been extensively evaluated. In this study, we investigated the effects of genetic mutations on myofiber function and fibrosis patterns in HCM.
View Article and Find Full Text PDFSci Rep
January 2025
School of New Energy, Longdong University, Qingyang, 745000, China.
In this work, taking wells LD1, LD2, and LY2 in the Laifeng-Xianfeng area as the research target, through core description, intensive core sampling, experimental analysis, imaging logging and other methods, the characteristics of graptolite zone development, organic carbon content, mineral composition, shale reservoir properties and the gas-bearing properties of the Wufeng-Longmaxi Formation shale are systematically analyzed. The main factors affecting the gas-bearing capacity of the Wufeng-Longmaxi Formation shale are extensively evaluated. The results reveal the following: ① The Wufeng-Longmaxi Formation shale, which was deposited in a deep-water shelf environment, has a large thickness (50-60 m) and a stable distribution.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
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