AI Article Synopsis
- Tuberculosis (TB) is a major global health concern, causing significant illness and death, and can manifest in various forms, including pulmonary (PTB) and extrapulmonary (EPTB) diseases.
- One rare hematological complication associated with TB is immune thrombocytopenic purpura (ITP), which was observed in a case involving a 22-year-old woman with ganglionic tuberculosis.
- Treatment of this case involved a combination of intravenous immunoglobulin, high-dose corticosteroids, and anti-tubercular therapy, leading to positive results.
Article Abstract
Tuberculosis (TB) is one of the leading infectious causes of morbidity and mortality worldwide. Either in its pulmonary (PTB) or extrapulmonary forms (EPTB), TB has a wide variety of manifestations, including hematological ones like thrombocytosis (especially in PTB) and thrombocytopenia (mainly with disseminated or miliary TB). Hematological manifestations are infrequently presenting features of TB, and within them, immune thrombocytopenic purpura (ITP)-associated TB is one of the rarest presenting features. We report a case of a 22-year-old woman with a diagnosis of ganglionic tuberculosis (GTB) presenting with ITP. The therapeutic approach was challenging and included the use, originally, of intravenous immunoglobulin 30 mg/day for five days and, posteriorly, of high-dose corticosteroids (dexamethasone 40 mg/day) and anti-tubercular therapy with satisfactory outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11235399 | PMC |
| http://dx.doi.org/10.7759/cureus.62074 | DOI Listing |
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