Lipschutz ulcer is a rare nonvenereal condition affecting predominantly young females who are not sexually exposed and can be triggered by various infectious agents, trauma, and drugs. It presents with single or multiple painful ulcers over labia minora, labia majora, vestibule, and lower part of the vagina and may be preceded by prodromal symptoms akin to influenza or mononucleosis. Diagnosis is based on specific criteria, which include age, ulcer characteristics, and absence of immunodeficiency. Management involves reassurance, supportive measures, and in severe cases, corticosteroids. This case highlights the importance of considering cytomegalovirus as a potential causative agent in Lipschutz ulcer and a cause for dysplasia.
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Lipschütz ulcer following first dose of COVID-19 tozinameran vaccine: Report of a case and review of a World Health Organization pharmacovigilance database.
Int J Gynaecol Obstet
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Department of Pharmacology and Pharmacovigilance Center of Nice, University Hospital of Nice, Nice, France.
Lipschütz ulcer (LU) is a condition known for painful vulvar ulcers, typically affecting young women and often linked to infectious agents. Recent reports have indicated a potential connection between LU and COVID-19 vaccination, particularly after the second or booster doses. This study presents a case of LU following the first dose of tozinameran in a young woman who had a previous SARS-CoV-2 infection and investigates similar cases globally.
View Article and Find Full Text PDFLipschütz ulcers: A diagnosis to be considered in the post-COVID-19 era.
Int J STD AIDS
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Servicio de Infectología, Clínica Especializada Condesa Iztapalapa, Ciudad de México, México.
Article Synopsis
- Lipschütz ulcers are a rare but significant type of genital ulcers that are often misdiagnosed or overlooked.
- The case study involves a 25-year-old woman with painful vulvar ulcers, general malaise, fatigue, and joint pain, who had mild COVID-19 symptoms for a month.
- After ruling out sexually transmitted infections and cytomegalovirus, a biopsy confirmed the diagnosis of Lipschütz ulcer.
NASPAG Clinical Consensus on Nonsexually Acquired Genital Ulcers (Vulvar Aphthous Ulcers).
J Pediatr Adolesc Gynecol
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Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:
The objective of this document is to provide guidance on the recognition, diagnosis and management of non-sexually acquired genital ulcers in the pediatric and adolescent patient. Commonly known as genital or vulvar aphthous ulcers, lesions are typically seen in the peri‑menarchal population, are exquisitely painful, generally self-limited and managed with supportive care. Details of ulcer physical appearance, proposed etiology and options for management are provided to familiarize clinicians with this entity, which can be alarming for patients and families.
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Dysplastic changes secondary to cytomegalovirus-induced Lipschutz ulcer: Unraveling complexity.
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Department of Dermatology, Venereology and Leprosy, Government Doon Medical College, Dehradun, Uttarakhand, India.
Lipschutz ulcer is a rare nonvenereal condition affecting predominantly young females who are not sexually exposed and can be triggered by various infectious agents, trauma, and drugs. It presents with single or multiple painful ulcers over labia minora, labia majora, vestibule, and lower part of the vagina and may be preceded by prodromal symptoms akin to influenza or mononucleosis. Diagnosis is based on specific criteria, which include age, ulcer characteristics, and absence of immunodeficiency.
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