Congenital syphilis (CS) is a vertically transmitted infection caused by the spirochete . It is seen rarely due to proper antenatal screening. Signs and symptoms appear within the first 2 years of life in early CS and after 2 years in late CS. Failure to diagnose and treat CS in its early stages can result in higher morbidity and mortality. Skin manifestations can guide toward the diagnosis of CS at an early stage. Here, we report a 2-day-old neonate who presented with acral peeling of skin along with respiratory distress and hepatosplenomegaly. Clinical suspicion of CS was made and subsequently confirmed by a positive venereal disease research laboratory test in both mother and child. The child was treated with aqueous crystalline penicillin G as per the CDC guidelines.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11233060 | PMC |
http://dx.doi.org/10.4103/ijstd.ijstd_15_24 | DOI Listing |
Asian J Surg
September 2024
Department of Pediatrics, First People's Hospital of Zigong City, Sichuan Province, Zigong, 643000, China. Electronic address:
J Dermatol
August 2024
Department of Dermatology, Self-Defense Forces Central Hospital, Tokyo, Japan.
Acral peeling skin syndrome (APSS; MIM 609796) is a rare genodermatosis characterized by painless focal cutaneous exfoliation of the dorsal hands and feet, typically displaying autosomal recessive inheritance. While cases associated with a founder mutation in TGM5 are relatively common in European Caucasian populations, no APSS cases have been reported from Japan or other East Asian countries. In contrast, Nagashima-type palmoplantar keratosis (NPPK; MIM 615598), caused by variants in SERPINB7, is relatively common in East Asia due to founder mutations.
View Article and Find Full Text PDFPediatr Dermatol
November 2024
Department of Internal Medicine, Division of Dermatology, Dell Medical School, University of Texas, Austin, Texas, USA.
Indian J Sex Transm Dis AIDS
June 2024
Department of Dermatology, All India Institute of Medical Sciences, Patna, Bihar, India.
Congenital syphilis (CS) is a vertically transmitted infection caused by the spirochete . It is seen rarely due to proper antenatal screening. Signs and symptoms appear within the first 2 years of life in early CS and after 2 years in late CS.
View Article and Find Full Text PDFActa Derm Venereol
April 2024
Department of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Umeå, Sweden.
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