AI Article Synopsis
- - Acetaminophen (APAP) overdose is the leading cause of acute liver failure (ALF) in the U.S., making timely intervention crucial.
- - Liver transplantation (LT) is a life-saving option for ALF, but its availability is often limited in healthcare settings.
- - A case study highlights a 44-year-old man with APAP-related ALF who successfully recovered liver function after treatment with the Molecular Adsorbent Recirculating System (MARS), though the device's role in ALF treatment is still unclear.
Article Abstract
Acetaminophen (APAP) overdose is the most common cause of acute liver failure (ALF) in the United States. Liver transplantation (LT) is potentially lifesaving for patients with ALF, but its feasibility in clinical practice is limited. Liver assist devices, such as the Molecular Adsorbent Recirculating System (MARS), are used in some centers as a "bridge" to liver transplantation or as a means of liver recovery, but their role in the treatment of ALF is not well-defined. We present the case of a 44-year-old man with APAP-associated ALF who experienced hepatic recovery after treatment with MARS.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236392 | PMC |
| http://dx.doi.org/10.14309/crj.0000000000001389 | DOI Listing |
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