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Potential of ginsenoside Rg1 to treat aplastic anemia mitogen activated protein kinase pathway in cyclophosphamide-induced myelosuppression mouse model.
World J Stem Cells
November 2024
Biological and Chemical Engineering, Hongik University, Sejong 30016, South Korea.
Aplastic anemia (AA) is a rare but serious condition in which the bone marrow fails to produce sufficient new blood cells, leading to fatigue, increased susceptibility to infection, and uncontrolled bleeding. In this editorial, we review and comment on an article by Wang published in 2024. This study aimed to evaluate the potential therapeutic benefits of ginsenoside Rg1 in AA, focusing on its protective effects and uncovering the underlying mechanisms.
View Article and Find Full Text PDF'Cheering on from the side-lines': The perceived impact of romantic partner's commentary and behaviour on maintaining women's appearance anxiety.
Psychol Psychother
December 2024
Department of Psychological Interventions, School of Psychology, University of Surrey, Guildford, Surrey, UK.
Article Synopsis
- The study investigates how romantic partner feedback affects women's appearance anxiety (AA), which is linked to body dysmorphic disorder.
- It involved semi-structured interviews with 13 cis-gender women, analyzing their experiences with partners' comments on appearance through cognitive behavioral theory.
- Four main themes emerged: the negative impact of critical comments, the potential for constructive feedback, misunderstandings between partners, and the supportive role partners can play in managing appearance anxiety.
Genome-Derived Ampullary Adenocarcinoma Classifier and Postresection Prognostication.
JAMA Surg
December 2024
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Article Synopsis
- Ampullary adenocarcinoma (AA) shows clinical and genetic diversity, and a new genomic classifier may improve patient classification beyond traditional methods, but it needs validation before being widely used.
- A study involving 192 patients with AA assessed the accuracy of this genomic classifier against standard histology to see if it could predict survival outcomes.
- Results indicated a 55% agreement between genomic and histological classifications; however, while histological subtypes did not predict survival, the genomic scores did correlate with survival probabilities, suggesting the genomic approach might be more effective.
The role of caregivers in mental health and child development policy and practice.
Lancet
September 2024
Clinton Health Access Initiative, Boston, MA, USA.
Aquablation in men with benign prostate hyperplasia: A systematic review and meta-analysis.
Curr Urol
March 2023
Department of Surgery, University of Melbourne, Austin Health, Melbourne, Australia.
Article Synopsis
- The study investigates how effective prostatic Aquablation is in relieving lower urinary tract symptoms in men with benign prostatic hyperplasia (BPH).
- A literature review covered seven clinical trials with a total of 551 patients, showing significant improvement in symptoms and urinary flow rate after treatment, lasting up to 12 months.
- Overall, Aquablation appears to reduce symptoms effectively while maintaining sexual function, but more research is necessary to validate these findings.
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