Substance use remains a critical concern in youth, necessitating early educational interventions to encourage informed decision-making. This study aimed to evaluate the effectiveness of a pilot health promotion and substance use prevention curriculum introduced at the third-grade level. Third-grade students from nine schools in South Dakota and Minnesota participated, with the curriculum's efficacy assessed via pre- and post-curriculum surveys evaluating students' knowledge of content included in the curriculum. Mean student age was 8.5 years old and average class size was 20 students. Results showed an increased understanding of basic substance use disorder concepts, an improved ability to identify different parts of the brain and identify harmful effects of substance use on the brain and body, and increased awareness of fentanyl as a dangerous substance. The differences between the pre-curriculum and post-curriculum were statistically significant, indicating learned concepts from the provided course content. This study highlights that a well-structured curriculum can bolster third graders' understanding about personal health, brain functions, safe medication use, and the potential harms from substance use.
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Matern Child Health J
January 2025
Department of Psychology, College of Arts and Sciences, Lehigh University, Bethlehem, USA.
Background: Research has increasingly explored maternal resilience or protective factors that enable women to achieve healthier maternal and child outcomes. However, it has not adequately examined maternal resilience using a culturally-relevant, socio-ecological lens or how it may be influenced by early-life stressors and resources. The current study contributes to the literature on maternal resilience by qualitatively exploring the salient multi-level stressors and resources experienced over the lifecourse by predominantly low-income and minoritized women.
View Article and Find Full Text PDFPharmacol Rep
January 2025
Research Laboratory CoreLab of the Medical University of Lodz, Łódź, Poland.
Background: The current study investigated the effects of high-fat diet on acute response to 3,4-methylenedioxypyrovalerone (MDPV) in mice. MDPV is a beta-cathinone derivative endowed with psychostimulant activity. Similarly to recreational substances, consumption of palatable food stimulates the mesolimbic dopaminergic system, resulting in neuroadaptive changes.
View Article and Find Full Text PDFNanomicro Lett
January 2025
College of Environmental Science and Engineering, State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, Siping Rd 1239, Shanghai, 200092, People's Republic of China.
Fluorinated gases (F-gases) play a vital role in the chemical industry and in the fields of air conditioning, refrigeration, health care, and organic synthesis. However, the direct emission of waste gases containing F-gases into the atmosphere contributes to greenhouse effects and generates toxic substances. Developing porous materials for the energy-efficient capture, separation, and recovery of F-gases is highly desired.
View Article and Find Full Text PDFJA Clin Rep
January 2025
Department of Anesthesiology and Critical Care Medicine, Hokkaido University Hospital, N14W5, Kita-ku, Sapporo, 060-8648, Japan.
Background: Plasma exchange (PE) removes high-molecular-weight substances and is sometimes used for antineutrophil cytoplasmic antibody-associated vasculitis (AAV) with alveolar hemorrhage. Hypotension during PE is rare, except in allergic cases. We report a case of shock likely caused by increased pulmonary vascular resistance (PVR) during PE.
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