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Impact of Sex on Infection Risk in Patients with Systemic Lupus Erythematosus.
Bioengineering (Basel)
January 2025
Allergy and Immunology Unit, Department of Medical Science, University of Turin, Mauriziano Hospital, 10128 Turin, Italy.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that exhibits considerable diversity in terms of both clinical and immunological manifestations. Since its female-to-male ratio is around 9:1, it is well recognized that systemic lupus erythematosus mostly affects women, especially those of childbearing age. There is a greater susceptibility to infections in adult patients with systemic lupus erythematosus (SLE) compared to the general population.
View Article and Find Full Text PDFCross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury.
J Neuroinflammation
January 2025
Spinal Cord and Brain Injury Research Center, Department of Physiology, College of Medicine, University of Kentucky, Lexington Kentucky, USA.
Objective: Therapeutic translation is challenging in spinal cord injury (SCI) and large animal models with high clinical relevance may accelerate therapeutic development. Pigs have important anatomical and physiological similarities to humans. Intraspinal inflammation mediates SCI pathophysiology.
View Article and Find Full Text PDFSex-based analysis of status epilepticus management and outcome: A cohort study.
Epilepsia
January 2025
Department of Clinical Neurosciences, Neurology Service, CHUV and University of Lausanne, Lausanne, Switzerland.
Status epilepticus (SE) is a neurological emergency with significant morbidity and mortality. The role of sex as a factor influencing the characteristics, treatment, and outcomes of SE has been scarcely addressed. This study investigates this variable regarding the clinical management and outcome among adult patients with SE.
View Article and Find Full Text PDFPrevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex, based on 134,603 refractive surgery candidates.
PLoS One
January 2025
Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Article Synopsis
- The study investigated the prevalence and factors associated with anisometropia (a condition where each eye has a different prescription) among 134,603 refractive surgery candidates in Germany from 2010 to 2020.
- Results indicated that 17.9% of the population had anisometropia, with variables like age, sex, and spherical/cylindrical ametropia significantly affecting its occurrence—different impacts were noted in hyperopes (farsighted individuals) versus myopes (nearsighted individuals).
- The findings reveal that increased cylindrical ametropia reduced anisometropia in hyperopes, while in myopes, it correlates positively with age and spherical power, showcasing the complexity
Individual sex-based variability to altitude training in elite badminton players.
J Sports Sci
January 2025
Laboratory Sport, Expertise and Performance (EA 7370), French Institute of Sport, Paris, France.
To assess how altitude training impacts force-velocity-power (F-V-P) profiling and muscular power and anaerobic capacity in elite badminton players in reference to intra- and inter-individual sex-based variability. Following a quasi-experimental design, 14 players (6 females, 8 males) from the French national badminton singles and doubles teams performed a 3-week 'living high-training high' camp at natural altitude (2320 m). F-V-P profile and Wingate anaerobic test were assessed Pre- and Post-intervention, using ANOVA repeated measures conventional statistics, with further estimation statistics to show the magnitude of the testing condition and visualize intra- and inter-individual responses.
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