Objective: The aim of the study is to investigate the effect and feasibility of using absorbable plate instead of frontal and orbital bar and inverted U-shaped osteotomy to correct the widening of orbital distance.
Methods: The surgical effect and feasibility of using absorbable plate instead of frontal and orbital bridge plus inverted U-osteotomy for orbital widening syndrome in seven cases between January 2019 and February 2022 were retrospectively analyzed. First, the surgical procedure for orbital hypertelorism was inverted U-shaped orbital osteotomy, and a frontal bone flap was removed, exposing the superior orbital margin and the orbital circumference, and the orbital bone was directly cut off by inverted U-shaped osteotomy. The widened bone in the middle of the orbit was removed, and a long absorbable plate was used to replace the orbitofrontal bridge. The two sides of the orbit were fixed on the absorbable plate, and the absorbable plate was fixed on the rear skull. The clinical effect of treatment, complications (such as cerebrospinal fluid leakage and infection), safety, and feasibility of surgery were evaluated.
Results: Using absorbable plate instead of fronto-orbital bridge achieved the effect of orbitofrontal bridge, without orbital distance widening, cerebrospinal fluid leakage, and intracranial infection. Operating time was reduced. There was no metal fixation, and there was no risk of a second operation.
Conclusions: The effect of replacing the frontal-orbital bridge with an absorbable plate and inverted U-shaped osteotomy is positive, the operation time is short, and the orbital distance is clearly improved. This approach can replace the traditional orbital-distance operation, and the incidence of postoperative cerebrospinal fluid leakage and infection is low. Long-term follow-up results are stable.
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http://dx.doi.org/10.1097/SAP.0000000000004029 | DOI Listing |
Front Immunol
December 2024
Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg-University (JGU) Medical Center, Mainz, Germany.
Background: The insulin-like growth factor 1 receptor (IGF-1R) and the thyrotropin receptor (TSH-R) are expressed on orbital cells and thyrocytes. These receptors are targeted in autoimmune-induced thyroid eye disease (TED). Effective therapeutic treatment of TED inhibits activation of the IGF-1R/TSH-R complex.
View Article and Find Full Text PDFOrthop Traumatol Surg Res
December 2024
Laboratoire ICube, Université de Strasbourg - CNRS, 4 rue de la Manufacture des Tabacs, 67000 Strasbourg, France; Service de Chirurgie Orthopédique et de Traumatologie, Hôpital de Hautepierre II, 1 Avenue Molière, 67098 Strasbourg Cedex, France. Electronic address:
Introduction: High tibial osteotomy (HTO) is indicated for managing isolated medial knee osteoarthritis in a young patient with a metaphyseal deformity of the proximal tibia. In a medial open-wedge HTO, maintaining the integrity of the hinge is crucial for consolidation and preservation of the correction. Based on a validated model and preliminary results, the objective of this work was to measure and monitor the distribution of mechanical load on a locking fixation plate and the lateral hinge of an HTO using a finite element (FE) model during different phases of consolidation evolution, simulating single leg weightbearing.
View Article and Find Full Text PDFFluids Barriers CNS
December 2024
Department of Mechanical Engineering, University of Minnesota, 111 Church St SE, Minneapolis, MN, 55455, USA.
Background: Growing evidence suggests that for rodents, a substantial fraction of cerebrospinal fluid (CSF) drains by crossing the cribriform plate into the nasopharyngeal lymphatics, eventually reaching the cervical lymphatic vessels (CLVs). Disruption of this drainage pathway is associated with various neurological disorders.
Methods: We employ a lumped parameter method to numerically model CSF drainage across the cribriform plate to CLVs.
Biotechniques
December 2024
Institute for Biomedicine and Glycomics and School of Environment and Science, Griffith University, Nathan, Qld, 4111, Australia.
Tyrosinase (TYR) inhibitors are required to treat skin hyperpigmentation. Currently live cell-based TYR assays and mushroom TYR assays are the common methods used to screen for TYR inhibitors. However, these methods are either time consuming and expensive or are not human TYR (TYR) specific.
View Article and Find Full Text PDFJ Hand Surg Am
December 2024
Orthopaedic Biomechanics Laboratory, Congress Medical Foundation, Pasadena, CA. Electronic address:
Purpose: The purpose of this study was to perform a biomechanical comparison of volar plate repair alone versus volar plate repair with suture tape augmentation in a hyperextension laxity injury model at the proximal interphalangeal (PIP) joint.
Methods: Ten matched cadaveric fingers were obtained from five cadavers (average age, 59 ± 7 years). The specimens underwent 5 and 10 N·cm of extension load at the PIP joint to measure the laxity of the intact joint.
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