Unraveling the biological link between diabetes mellitus and prostate cancer: Insights and implications.

World J Diabetes

Department of Interventional Oncology, Municipal Hospital Affiliated to Taizhou University, Taizhou 318000, Zhejiang Province, China.

Published: June 2024

This article is a comprehensive study based on research on the connection between diabetes mellitus (DM) and prostate cancer (PCa). It investigates the potential role of DM as an independent risk factor for PCa, delving into the biological links, including insulin resistance and hormonal changes. The paper critically analyzes previous studies that have shown varying results and introduces mendelian randomization as a method for establishing causality. It emphasizes the importance of early DM screening and lifestyle modifications in preventing PCa, and proposes future research directions for further under-standing the DM - PCa relationship.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229951PMC
http://dx.doi.org/10.4239/wjd.v15.i6.1367DOI Listing

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