One of the most difficult challenges that military personnel face when operating in foreign countries is clear and successful communication with the local population. To address this issue, the Defense Advanced Research Projects Agency (DARPA) is funding academic institutions and industrial organizations through the Spoken Language Communication and Translation System for Tactical Use (TRANSTAC) program to develop practical machine translation systems. The goal of the TRANSTAC program is to demonstrate capabilities to rapidly develop and field free-form, two-way, speech-to-speech translation systems that enable speakers of different languages to communicate with one another in real-world tactical situations without an interpreter. Evaluations of these technologies are a significant part of the program and DARPA has asked the National Institute of Standards and Technology (NIST) to lead this effort. This article presents the experimental design of the TRANSTAC evaluations and the metrics, both quantitative and qualitative, that were used to comprehensively assess the systems' performance.
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http://dx.doi.org/10.1016/j.csl.2011.05.001 | DOI Listing |
STAR Protoc
January 2025
School of Public Health, Chongqing Medical University, Chongqing 400016, China; Chongqing Miankai Biotechnology Research Institute Co., Ltd., Chongqing 400025, China. Electronic address:
The recombinase polymerase amplification (RPA)-CRISPR-Cas12a-FQ system enables sensitive detection of environmental DNA (eDNA) in rare fish species. Here, we present a protocol for eDNA amplification and Cas12a for target recognition using RPA. We describe steps for identifying a target site, synthesis and purification of CRISPR RNA (crRNA), and RPA isothermal amplification.
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Translational Research Support Section, National Cancer Center Hospital East, Chiba, Japan.
Early cancer detection substantially improves the rate of patient survival; however, conventional screening methods are directed at single anatomical sites and focus primarily on a limited number of cancers, such as gastric, colorectal, lung, breast, and cervical cancer. Additionally, several cancers are inadequately screened, hindering early detection of 45.5% cases.
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Advanced Medical Devices Laboratory, Kyushu University, Nishi-ku, Fukuoka, 819-0382, Japan.
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Methods: We propose a modified Transformer model with the architecture comprising no positional encoding, 5 fully connected layers, 1 encoder, and 3 decoders.
J Cell Mol Med
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Department of Medical Biology, Faculty of Medicine, Kutahya Health Sciences University, Kutahya, Turkey.
Chemotherapy is a potent tool against cancer, but drug resistance remains a major obstacle. To combat this, understanding the molecular mechanisms behind resistance in cancer cells and the protein expression changes driving these mechanisms is crucial. Targeting the Ubiquitin-Proteasome System (UPS) has proven effective in treating multiple myeloma and shows promise for solid tumours.
View Article and Find Full Text PDFBMC Health Serv Res
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Department of School and Social Adaptation Studies, Faculty of Education, Université de Sherbrooke, Sherbrooke, Canada.
Background: The COVID-19 pandemic necessitated the rapid availability of evidence to respond in a timely manner to the needs of practice settings and decision-makers in health and social services. Now that the pandemic is over, it is time to put in place actions to improve the capacity of systems to meet knowledge needs in a situation of crisis. The main objective of this project was thus to develop an action plan for the rapid syntheses of evidence in times of health crisis in Quebec (Canada).
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