AI Article Synopsis
- Calcifications found on mammograms can sometimes signal systemic diseases rather than breast cancer, prompting further histologic testing.
- A case study describes a patient with bilateral calcifications that were ultimately diagnosed as amyloidosis via core biopsy.
- Awareness of the patient's existing condition, systemic light chain amyloidosis, led to the use of specific staining techniques to confirm the diagnosis, highlighting the importance of understanding systemic diseases in radiology.
Article Abstract
Calcifications on mammography from systemic disease at times meet diagnostic criteria for histologic sampling to exclude malignancy. We present a case of bilateral groups of new calcifications on mammography that yielded amyloidosis on core biopsy. Awareness of our patient's known diagnosis of systemic light chain amyloidosis (AL) prompted use of Congo red staining to confirm the histologic diagnosis. Knowledge of systemic diseases with possible manifestations on mammography can facilitate cogent and clinically relevant radiology-pathology correlation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11231514 | PMC |
| http://dx.doi.org/10.1016/j.radcr.2024.05.083 | DOI Listing |
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