Silicon nitride (SiN) is a bioceramic material with potential applications. Customization and high reliability are the foundation for the widespread application of SiN bioceramics. This study constructed a new microwave heating structure and successfully prepared 3D printed dense SiN materials, overcoming the adverse effects of a large amount of 3D printed organic forming agents on degreasing and sintering processes, further improving the comprehensive performance of SiN materials. Compared with control materials, the 3D printed SiN materials by microwave sintering have the best mechanical performance: bending strength is 928 MPa, fracture toughness is 9.61 MPa·m. Meanwhile, it has the best biocompatibility and antibacterial properties, and cells exhibit the best activity on the material surface. Research has shown that the excellent mechanical performance and biological activity of materials are mainly related to the high-quality degreasing, high cleanliness sintering environment, and high-quality liquid-phase sintering of materials in microwave environments.
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http://dx.doi.org/10.1038/s41598-024-66942-w | DOI Listing |
Waste Manag
December 2024
College of Environmental Science and Engineering and Key Laboratory of Environmental Biology and Pollution Control (Ministry of Education), Hunan University, Changsha 410082, PR China.
With the exponential growth of global photovoltaic (PV) installed capacity, the quantity of discarded PV modules continues to rise. This study innovatively explored the sustainable recovery and utilization of raw materials from discarded solar panels, focusing on the transformation of recycled silicon into microporous silica nanoparticles (MSN). Low toxic organic solvent ethyl acetate (EA) was for the first time utilized to reduce the viscosity of ethylene-vinyl acetate (EVA) and facilitated its removal.
View Article and Find Full Text PDFVirol Sin
December 2024
College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China. Electronic address:
Traditional Chinese medicine has unique advantages in preventing and treating COVID-19, and Fuzheng Jiedu decoction (FZJDD) was reported to be effective against COVID-19 in clinical trials. To investigate the potential mechanisms and material basis of FZJDD against SARS-CoV-2, we performed SARS-CoV-2 target protein inhibition analyses and a metabolite full spectrum analysis of FZJDD. Interestingly, FZJDD was found to block the binding of SARS-CoV-2 Spike protein with the receptor ACE2 and inhibit the activity of SARS-CoV-2 3CLpro.
View Article and Find Full Text PDFTalanta
December 2024
Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences & Chongqing School, University of Chinese Academy of Science, Chongqing, 400714, PR China. Electronic address:
Owing to the facile fabrication and surface modification, the cost-effective polymer nanopores are widely employed in unimolecular determination of biomacromolecules and selective sensing of small molecules, nanoparticles and biomarkers. However, the documented polymer nanochannels are generally microscale in length with low spatial resolution. We herein synthesized azobenzene side-chain polymer (Azo-PMA) and spin-coated on silicon nitride membrane to obtain a polymer film of nanoscale thickness for further nanopore generation via controlled dielectric breakdown (CDB) approach.
View Article and Find Full Text PDFClin Auton Res
December 2024
Facultad de Medicina, Universidad Autónoma de Sinaloa, C. Sauces, s/n, 80019, Culiacán, SIN, Mexico.
Purpose: The parasympathetic effects of the sphenopalatine ganglion (SPG) on the cerebral vasculature provide a compelling rationale for its therapeutic application in cerebrovascular ischemia. In recent years, attempts have been made to stimulate the SPG to achieve beneficial effects on cerebral circulation.
Methods: This review synthesizes the available publications on SPG stimulation.
JMIR Rehabil Assist Technol
December 2024
School of Nursing and Midwifery, Deakin University, Burwood, Melbourne, Australia.
Background: Cognitive frailty is known to be associated with both nutrition and cognitive training. However, effective treatments that engage older adults with cognitive frailty in both the Mediterranean diet and cognitive training are lacking.
Objective: This study aims to examine the feasibility and preliminary effects of Gamified Home-Based Cognitive-Nutritional (GAHOCON) on older adults with cognitive frailty, focusing on Mediterranean diet knowledge, adherence to the Mediterranean diet, cognitive function, physical frailty, grip strength, walking speed, memory, and body composition.
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