Electroorganic synthesis has become an exciting tool for the asymmetric conversion of pro-chiral compounds. Herein, we introduced a wireless methodology based on bipolar electrochemistry in synergy with the enantioselective capabilities of inherently chiral oligomers to induce an umpolung chirality transfer. This was exemplified by the electro-conversion of a racemic mixture of lansoprazole to an -enriched solution of a single antipode.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392033PMC
http://dx.doi.org/10.1039/d4cc02406kDOI Listing

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