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Serum Vitamin D and Zinc Levels in Children with Urinary Tract Infection without Confounding Factors: A Case-Control Study. | LitMetric

AI Article Synopsis

  • * A study examined serum levels of zinc and vitamin D in 40 healthy children and 40 children with UTIs, finding significant differences in vitamin D and zinc levels between the two groups.
  • * The results indicated that low levels of these nutrients may increase the risk of UTIs in children, suggesting that zinc and vitamin D supplementation could help prevent infections and support treatment.

Article Abstract

Background: Urinary tract infections (UTIs) are extremely prevalent bacterial infections among children. They have numerous potential causes. Without proper diagnosis and treatment, UTIs can lead to serious complications in children, including impaired growth, high blood pressure, protein in urine, and eventual chronic kidney disease. Zinc and vitamin D in sufficient concentrations help to maintain the health of the immune system. Therefore, their deficiency can cause various infections. Several factors can contribute to the development of UTIs. This article deals with the role of zinc and vitamin D as immune markers in UTI in children without other risk factors.

Methods: In this case-control study, serum zinc and vitamin D levels without any other risk factors were examined in 40 healthy children and 40 children with UTIs. Data analysis was done through SPSS 26 using the chi-square, the Fisher's exact, and independent t tests.

Results: The study findings demonstrated a statistically significant distinction between the 2 groups regarding serum vitamin D and zinc levels ( < 0.001); 80% of children with UTIs and 17.5% in the healthy group had vitamin D deficiency. Also, 60% of the urinary infection group had zinc deficiency, whereas 17.5% of the healthy group had it.

Conclusion: Low serum zinc and vitamin D levels may increase susceptibility to pediatric UTI. Given the data, supplementation with zinc and vitamin D could play a significant role in treating active infections and preventing recurrence in susceptible children.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11230592PMC
http://dx.doi.org/10.47176/mjiri.38.36DOI Listing

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