AI Article Synopsis
- Phthalates (PAEs) are commonly used in plastics due to their plasticity, but their toxicity has led to the rise of alternatives like DINCH and DEHTP.
- Both classic PAEs and their newer alternatives are found in diverse environmental settings, from air to water, raising concerns about their endocrine-disrupting effects on wildlife and human health.
- Current research mainly focuses on traditional PAEs, highlighting the need to understand the behavior and risks associated with emerging alternatives as they become more prevalent in the environment.
Article Abstract
Because of their excellent plasticity, phthalates or phthalic acid esters (PAEs) are widely used in plastic products. However, due to the recognized toxicity of PAEs and legislative requirements, the production and use of emerging PAE alternatives have rapidly grown, such as di-isononyl cyclohexane-1,2-dicarboxylate (DINCH) and di(2-ethylhexyl) terephthalate (DEHTP) which are the primary replacements for classic PAEs. Nowadays, PAEs and emerging PAE alternatives are frequently found in a variety of environmental media, including the atmosphere, sludge, rivers, and seawater/sediment. PAEs and emerging PAE alternatives are involved in endocrine-disrupting effects, and they affect the reproductive physiology of different species of fish and mammals. Therefore, their presence in the environment is of considerable concern due to their potential effects on ecosystem function and public health. Nevertheless, current research on the prevalence, destiny, and conduct of PAEs in the environment has primarily focused on classic PAEs, with little attention given to emerging PAE alternatives. The present article furnishes a synopsis of the physicochemical characteristics, occurrence, transport, fate, and adverse effects of both classic PAEs and emerging PAE alternatives on organisms in the ecosystem. Our analysis reveals that both classic PAEs and emerging PAE alternatives are widely distributed in all environmental media, with emerging PAE alternatives increasingly replacing classic PAEs. Various pathways can transform and degrade both classic PAEs and emerging PAE alternatives, and their own and related metabolites can have toxic effects on organisms. This research offers a more extensive comprehension of the health hazards associated with classic PAEs and emerging PAE alternatives.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11356-024-34213-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Implementing and evaluating the comprehensive integration of physical activity into a major health system: study design and protocol.
BMJ Open
January 2025
Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, South Carolina, USA
Introduction: The healthcare sector has great potential for promoting physical activity (PA) for chronic disease prevention, treatment and management; however, multiple adoption and implementation barriers exist, ranging from practice integration to information flow. In 2016, Exercise is Medicine Greenville (EIMG), a comprehensive clinic-to-community approach that involves PA assessment, recommendation and/or prescription and provider-based referral of patients to community-based PA programmes, was launched by Prisma Health in Greenville, South Carolina, USA. Since inception, variability has emerged in adoption and implementation, impacting patient reach, referral rates and engagement in the community-based PA programmes, highlighting the need for closer evaluation and refinement of strategies to maximise programme impact.
View Article and Find Full Text PDFThe characteristics of phthalate acid esters and bisphenol A in PM of a petrochemical city: Concentrations, compositions, and health risk assessment in Dongying.
Environ Pollut
December 2024
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, 10012, China.
Phthalate acid esters (PAEs) and bisphenol A (BPA) are recognized as common endocrine disruptors associated with various adverse effects on human health. However, limitations in existing systematic studies, particularly in air detection, have raised concerns about potential health risks from inhalation exposure. In this study, PM samples were collected in Dongying, a petrochemical city, from October 27 to December 6, 2021.
View Article and Find Full Text PDFFertilizer Addition Modifies Utilization of Different P Sources in Upland Rice on Strongly P-fixing Andosols.
J Soil Sci Plant Nutr
May 2024
Group of Isotope Biogeochemistry and Gas Fluxes, Leibniz Centre for Agricultural Landscape Research (ZALF) E.V., Müncheberg, Germany.
Aims: High Phosphorus (P) efficiencies such as internal P utilization efficiency (PUE) and P acquisition efficiency (PAE) are crucial for upland rice production, particularly on highly P-fixing soils like Andosols. While the effect of root traits associated with high PAE in upland rice has been studied intensively, less attention has been given to the origin of P (native soil-P versus fertilizer-P) taken up by plants when evaluating differences in P efficiency. Here we aim to evaluate the efficiency of different upland rice genotypes to acquire native soil-P and fertilizer-P.
View Article and Find Full Text PDFA pain research strategy for Europe: A European survey and position paper of the European Pain Federation EFIC.
Eur J Pain
January 2025
UCD School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.
Background: Pain is the leading cause of disability and reduced quality of life worldwide. Despite the increasing burden for patients and healthcare systems, pain research remains underfunded and under focused. Having stakeholders identify and prioritize areas that need urgent attention in the field will help focus funding topics, reduce 'research waste', improve the effectiveness of pain research and therapy and promote the uptake of research evidence.
View Article and Find Full Text PDFOral ciprofloxacin biofilm activity in a catheter-associated urinary tract infection model.
J Antimicrob Chemother
November 2024
Department of Infectious Diseases, Alfred Hospital and School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.
Article Synopsis
- Catheter-associated urinary tract infections (CA-UTIs) are common hospital infections; this study evaluates the effectiveness of ciprofloxacin against these infections using an in vitro model.
- Researchers tested three standard bacterial strains and 45 clinical isolates to measure biofilm mass and bacterial density before and after treatment with ciprofloxacin.
- Results showed that while K. pneumoniae biofilms were more resistant to disruption, E. coli showed persistent growth in the bladder, and Pseudomonas aeruginosa had higher rates of ciprofloxacin resistance.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!