Background: Traditional surgical approaches excluded septoplasty at primary cleft lip reconstruction due to concerns about restricted nasal and midfacial growth. Modern opinion in the treatment of cleft lip has increasingly employed primary septoplasty; this scoping review and historical perspective aims to chronicle the evolution of septoplasty in patients born with cleft lip and palate and discuss current evidence.
Methods: The historical perspective explicitly contrasts American and European perceptions of septoplasty in cleft lip deformity and the competing anatomical theories of the role of the septum on midfacial and nasal growth. For the scoping review, articles were extracted from Embase, PubMed, and Medline, as well as manual searches of reference lists. Results were compiled, grouped, and appraised by date, outcomes, and historical significance. Inclusion criteria consisted of children who underwent primary septoplasty for any indication and were followed up on outcomes of facial growth and nasal function. Literature reviews, opinion articles, case reports, guidelines, or studies not available in English or online were excluded.
Results: Evolving anatomical theories relating to midfacial growth in the mid-late 20th century underpinned a progressive ideological shift on the safety and efficacy of septoplasty in children. This is supported by our scoping review, which included 23 articles mutually selected for inclusion by 2 blinded assessors. Several competing methods have been employed to measure endpoints on facial growth and nasal function, but generally indicate primary septoplasty is successful in improving nasal function and preserving midfacial growth.
Conclusion: Perceptions towards septoplasty on facial growth in the pediatric population have transformed significantly and suggest a growing acceptance of primary septoplasty techniques in patients born with a cleft lip.
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http://dx.doi.org/10.1097/SCS.0000000000010454 | DOI Listing |
BMJ Case Rep
January 2025
Department of Speech Language Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India
Cleft lip and palate (CLP) significantly impact speech and language development in children. In remote areas, access to specialised services is often limited, necessitating innovative approaches for effective service delivery. This case report explores the potential of tele-supervised intervention provided by community-based rehabilitation workers (CBRWs) to enhance communication outcomes for children with CLP.
View Article and Find Full Text PDFOdontology
January 2025
Department of Pediatric Dentistry, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, São Paulo, Brazil.
This study aimed to compare the dimensional alterations of the dental arches and the palate symmetry in patients with unilateral complete cleft lip and palate before and after the performance of primary surgeries by different surgical techniques. The sample was divided into Group 1, G1 - cheiloplasty (Millard technique) and single-stage palatoplasty (von Langenbeck technique); Group 2, G2 - cheiloplasty (Millard technique) and two-stage palatoplasty (Hans Pichler and Sommerlad techniques). The digital dental models were evaluated before (Time 1, T1) and after (Time 2, T2) primary surgeries.
View Article and Find Full Text PDFMaxillofac Plast Reconstr Surg
January 2025
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Damascus University, Damascus, Syrian Arab Republic.
Background: An orofacial cleft significantly impacts the oral health-related quality of life of children and teenagers. Secondary reconstruction is a more complex procedure due to tissue deficiency and scarring. The study aimed to evaluate the use of Pfeifer's wave-line incision method and the rotational flap method in the secondary reconstruction of unilateral lip clefts in patients with unilateral cleft lip and ala nasi aged 5-25 years utilizing anthropometry assessment.
View Article and Find Full Text PDFNeurosurg Focus
January 2025
3ENT and Head and Neck Research Center and Department, The Five Senses Health Institute, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Objective: Craniofacial clefts, characterized by congenital disruptions in the development of facial and cranial tissues, often present alongside orbital hypertelorism (ORH), an abnormal increase in the interorbital distance. These conditions pose significant challenges in craniofacial surgery due to the complex anatomical and functional considerations involved. This single-center cohort study retrospectively analyzed 22 patients diagnosed with craniofacial cleft syndromes and ORH who were treated at the Craniofacial Centre, Fatima Plastic and Reconstructive Surgery Hospital between July 2016 and October 2023.
View Article and Find Full Text PDFImeta
December 2024
State Key Laboratory of Cultivation Base of Research, Prevention and Treatment for Oral Diseases Nanjing Medical University Nanjing China.
This study investigated pathogenic genes associated with non-syndromic cleft lip with or without cleft palate (NSCL/P) through transcriptome-wide association studies (TWAS). By integrating expression quantitative trait loci (eQTL) data with genome-wide association study (GWAS) data, we identified key susceptibility genes, including . Notably, the variant rs12884809 G>A was associated with an increased risk of NSCL/P by enhancing the binding of the transcription factor ELK1 to the promoter, thereby activating its expression.
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