AI Article Synopsis
- Renal aspergillosis is a rare but serious complication following kidney transplants, highlighted by the case of a 45-year-old man who had a transplant from his mother.
- After initially recovering, the patient faced kidney dysfunction and signs of systemic infection due to active antibody-mediated rejection, leading to a diagnosis of renal aspergillosis.
- Despite aggressive treatment efforts, the patient's condition worsened to renal graft cortical necrosis, resulting in the need for nephrectomy, emphasizing the importance of early diagnosis and intervention in transplant patients.
Article Abstract
Renal aspergillosis is a rare yet potentially devastating complication following renal allograft transplantation. We present the case of a 45-year-old male with a history of crescentic IgA nephropathy who underwent renal allograft transplantation from his mother. Despite initial favorable progress, he developed post-transplant renal dysfunction attributed to active antibody-mediated rejection. Subsequently, he presented with signs of systemic infection and graft dysfunction, leading to the diagnosis of renal aspergillosis. Despite aggressive management, including antifungal therapy and cessation of immunosuppression, the patient progressed to renal graft cortical necrosis, necessitating nephrectomy. This case underscores the challenges in diagnosing and managing renal aspergillosis in transplant recipients and highlights the importance of early recognition and prompt intervention to improve outcomes in such cases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227294 | PMC |
| http://dx.doi.org/10.7759/cureus.61817 | DOI Listing |
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