AI Article Synopsis
- - The study investigates the antihyperglycemic effects of an ethanolic extract from plant roots, traditionally used in Uzbek medicine to manage diabetes.
- - Findings showed that the extract significantly reduced glucose levels by inhibiting reactive oxygen species, activating glucose transporters, and suppressing enzymes like α-amylase and α-glucosidase.
- - This research connects traditional healing practices with scientific evidence, highlighting the extract's potential for developing future diabetes medications.
Article Abstract
Plant extracts have been widely used in traditional medicine to prevent diabetes. The present study aimed to examine the antihyperglycemic properties of an ethanolic extract from roots. evaluation revealed that treatment with the extract resulted in significant reactive oxygen species inhibition, glucose binding, glucose transporter activation, and suppression of α-amylase and α-glucosidase. Moreover, the treatment with 100 mg/kg of extract dramatically decreased glucose levels in glucose-, alloxan-, or adrenaline-induced diabetic rats. The information gathered in this study bridges the knowledge gap between traditional healers in Uzbekistan who utilize and its potential for future medication development.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223926 | PMC |
| http://dx.doi.org/10.3746/pnf.2024.29.2.135 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!