Dysmenorrhea severity in war refugees with hypertension: a cross-talk with antihypertensives and analgesics.

Afr Health Sci

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University -Irbid, Jordan.

Published: December 2023

Background: Dysmenorrhea is the most common gynecological condition among women of reproductive age. Investigating the cross-talk between hypertension and dysmenorrhea is attractive and understudied, moreover, menstrual health is poorly studied in refugees.

Objectives: The present study aims at examining the association between dysmenorrhea severity and antihypertensives and analgesics namely acetaminophen and Non-Steroidal Anti-inflammatory Drugs (NSAIDs) used by traumatized Syrian war refugees with hypertension.

Methods: This is a cross-sectional study recruiting Syrian female refugees with hypertension. A structured questionnaire probed their demographics and clinical data. Dysmenorrhea severity was assessed using the WaLIDD (working ability, location, intensity, days of pain, dysmenorrhea) self-report scale.

Results: Data were analysed from 125 patients, almost half were diabetic, 47 (37.6%) had dyslipidemia, 59 (47%) reported using β-blockers, 56 (44.8%) reported using ACEIs/ARBs, 43 (34.2) reported using CCBs and 30 (25%) were using diuretics. According to the multivariate binary logistic regression, severe dysmenorrhea was associated with acetaminophen OR 6.5, 95%CI (1.39-30.55), p=0.02 and NSAIDs use OR 2.97, 95%CI (1.28-6.89), p=0.02. Antihypertensive drugs were not associated with dysmenorrhea severity.

Conclusion: Determinants of severe dysmenorrhea in patients with hypertension need more study, herein we report that analgesics but not antihypertensives are not associated with dysmenorrhea severity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11225439PMC
http://dx.doi.org/10.4314/ahs.v23i4.47DOI Listing

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