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Assessment of the Operational Aspects of Health and Wellness Centers in Randomly Selected Blocks of Eastern India.
Cureus
December 2024
Community Medicine, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Introduction Launched in 2018, by the Government of India, the Health and Wellness Centers (HWCs) initiative under the Ayushman Bharat program aims to transform India's primary healthcare system. This study evaluates the functioning of Health and Wellness Centres (HWCs) in random blocks of Patna, Bihar, focusing on service availability, infrastructure, manpower challenges, and overall effectiveness in meeting healthcare needs. Methodology The assessment aimed to understand the current state of functioning of 16 HWCs and identify areas for improvement through a Strengths, Weaknesses, Opportunities, Threats (SWOT) analysis.
View Article and Find Full Text PDFThe utilization of microbial cell-free DNA next-generation sequencing for the detection of human herpesvirus-8 in a quaternary care center.
Ther Adv Infect Dis
January 2025
Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
Background: Human herpesvirus-8 (HHV8) can present with cutaneous or extracutaneous manifestations. While violaceous skin lesions characterize cutaneous Kaposi sarcoma, extracutaneous HHV8 is challenging to diagnose due to nonspecific symptoms.
Objectives: We evaluated the role of microbial cell-free DNA next-generation sequencing (mcfDNA NGS) in diagnosing HHV8-related illness.
Flies as carriers of antimicrobial resistant (AMR) bacteria in Nigerian hospitals: A workflow for surveillance of AMR bacteria carried by arthropod pests in hospital settings.
Environ Int
January 2025
Ineos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, United Kingdom; Division of Infection and Immunity, Department of Medical Microbiology, Heath Campus, Cardiff University, Cardiff, United Kingdom. Electronic address:
The dissemination of antimicrobial resistant (AMR) bacteria by flies in hospitals is concerning as nosocomial AMR infections pose a significant threat to public health. This threat is compounded in low- and middle-income countries (LMICs) by several factors, including limited resources for sufficient infection prevention and control (IPC) practices and high numbers of flies in tropical climates. In this pilot study, 1,396 flies were collected between August and September 2022 from eight tertiary care hospitals in six cities (Abuja, Enugu, Kaduna, Kano, Lagos and Sokoto) in Nigeria.
View Article and Find Full Text PDFImmunoblot evaluation of rubella humoral immunity in Portuguese women with negative or low-positive rubella IgG.
Diagn Microbiol Infect Dis
January 2025
CHRC, NOVA Medical School Faculdade de Ciências Médicas, NMS FCM, Universidade NOVA de Lisboa; Campo dos Mártires da Pátria 130, 1169-056 Lisboa, Portugal.
Despite its low incidence in Europe, rubella's immune status is still routinely assessed using commercial immunoassays. However, some discrepancies have been observed between these tests and the Immunoblot. The main objective of this study is to evaluate, by a commercial immunoblot, the immune status of a female population that had previously presented negative, low-positive, or equivocal rubella IgG with a commercial immunoassay.
View Article and Find Full Text PDFJapanese encephalitis (JE) is a zoonotic disease caused by the Japanese encephalitis virus (JEV), belonging to the family. Diagnosis of Japanese encephalitis (JE) based on clinical signs alone is challenging due to the high proportion of subclinical cases. The Plaque Reduction Neutralization Test (PRNT) is considered the gold standard for detecting JE-specific antibodies because of its high specificity.
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