AI Article Synopsis

  • The study aims to evaluate agreement among dermatologists on how to manage and prevent irritation from topical retinoids used for treating facial and trunk acne, aiming to reduce treatment dropouts.
  • A questionnaire derived from existing literature was given to 133 dermatologists, revealing that 82.3% of the 34 recommendations received significant agreement, especially on patient education and application methods.
  • The findings suggest that irritation is a common and manageable response to retinoids, and following appropriate guidelines can help patients stick with their treatments.

Article Abstract

Objective: To assess the level of agreement on various prevention and management strategies for irritation caused by topical retinoids in facial and trunk acne in an attempt to alleviate it and minimize treatment discontinuations as much as possible.

Method: After reviewing the scientific medical literatura currently available, 4 different areas of uncertainty in the management of irritation caused by topical retinoids in acne were identified. A questionnaire with 34 recommendations was created and evaluated by a group of 133 dermatologists (Delphi methodology).

Results: In 82.3% of the recommendations (28 out of 34), some level of agreement was reached (≥85% agreement in 22 recommendations and≥70% agreement in 6). The results with the highest level of agreement focused on specific patient education strategies (explaining that irritation is an expected reaction at the beginning of treatment and tends to decrease over time), gradual and/or spaced application of topical retinoids (at night time to prevent and/or reduce skin irritation), and the importance of using adjuvant products, specific for acne-prone skin, hydration, photoprotection, and skin cleansing. These recommendations reflect a comprehensive approach to managing irritation associated with topical retinoids and promoting long-term adherence.

Conclusions: Skin irritation caused by topical retinoids in facial and trunk acne is an expected, mild, and controllable reaction if proper prevention and management guidelines are followed, meaning that it should not be a reason for treatment discontinuation.

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Source
http://dx.doi.org/10.1016/j.ad.2024.07.010DOI Listing

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