AI Article Synopsis
- The review evaluates the importance of using optical coherence tomography angiography (OCTA) to assess the radial peripheral capillary (RPC) network in patients with COVID-19 confirmed by PCR tests.
- It highlights how factors like hypoxia, inflammation, and a hypercoagulable state negatively impact the RPC network, showing decreased parameters both early in the infection and months later.
- The study suggests that OCTA should be used in COVID-19 patients to monitor ocular function and potential adverse effects on the optic nerve and retina, calling for ongoing assessments.
Article Abstract
Purpose: This review aimed to evaluate the significance of assessing radial peripheral capillary (RPC) network parameters by optical coherence tomography angiography (OCTA) in patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection confirmed by polymerase chain reaction.
Methods: A literature search was conducted in the PubMed database to select high-quality reviews and original articles on the use of OCTA for visualizing the RPC network and calculating RPC parameters.
Results: The study revealed that systemic hypoxia, hypercoagulable state, and inflammation affect the RPC network in patients with coronavirus disease 2019 (COVID-19). Reduced RPC parameters were observed early in the course of SARS-CoV-2 infection and after several months of follow-up. Additionally, there was a correlation between reduced RPC parameters and subsequent thinning of the retinal nerve fiber layer.
Conclusions: The OCTA examination of the retina and optic disc should be considered in patients with a history of COVID-19 to assess the impact of systemic hypoxia and inflammation on ocular function. Follow-up assessment of these patients is also necessary to understand the potential consequences of ischemia affecting the optic nerve, retina, and choroid.
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| http://dx.doi.org/10.1016/j.advms.2024.07.001 | DOI Listing |
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