Hydroxyurea in Sickle Cell Disease and Invasive Bacterial Infections: A Case-Control Study.

J Pediatric Infect Dis Soc

Department of Paediatrics, Hôpital Paris Saclay, France.

Published: September 2024

Hydroxyurea decreases painful events among children with sickle cell disease (SCD) but could increase the risk of infections in treated patients through leucopenia. We performed a case-control study, comparing hydroxyurea treatment for SCD in cases with an invasive bacterial infection and in controls without infection. No difference was found.

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Source
http://dx.doi.org/10.1093/jpids/piae071DOI Listing

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