AI Article Synopsis

  • A report revealed that cyclooxygenase-2 inhibitors can help prevent cystitis glandularis recurrence after surgery.
  • A case study of a 45-year-old man showed he had cystitis glandularis with large tumors causing urination issues, which improved after taking a cyclooxygenase-2 inhibitor for six weeks.
  • The findings suggest that using cyclooxygenase-2 inhibitors might be a valuable treatment option for managing cystitis glandularis.

Article Abstract

Introduction: A previous report has shown that cyclooxygenase-2 inhibitors can prevent the recurrence of cystitis glandularis postoperatively. Herein, we present a case of cystitis glandularis in which the tumor volume was markedly reduced by preoperative oral administration of a cyclooxygenase-2 inhibitor.

Case Presentation: A 45-year-old man with voiding difficulty and lower abdominal pain during urination was referred to our hospital. Cystoscopy revealed multiple cystitis glandularis-like edematous masses on the trigone and the neck of the bladder, completely involving the bilateral ureteral orifices. Cyclooxygenase-2 inhibitor was orally administered at the patient's request. Six weeks later, the tumor volume was markedly reduced, bilateral ureteral orifices were identified, and the voiding difficulty and pain on urination disappeared. Complete transurethral resection of the residual tumor was performed, and the pathological diagnosis was intestinal-type cystitis glandularis.

Conclusion: Cyclooxygenase-2 inhibition can be considered a useful therapeutic strategy for cystitis glandularis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221942PMC
http://dx.doi.org/10.1002/iju5.12728DOI Listing

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