AI Article Synopsis

  • Angioimmunoblastic T-cell lymphoma (AITL) is a rare form of non-Hodgkin lymphoma, illustrated through a case involving a 60-year-old female with symptoms like fatigue, fever, weight loss, and swollen lymph nodes for six months.
  • Despite extensive lab tests and imaging, the initial lymph node biopsy was inconclusive, but further PET-CT revealed a treatable adenopathy that confirmed the AITL diagnosis.
  • The patient's condition worsened despite chemotherapy, leading to a focus on symptomatic treatment, ultimately resulting in her passing six months after diagnosis due to the challenges in identifying this complex disease.

Article Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is a rare type of non-Hodgkin lymphoma (NHL). We present a case of a 60-year-old female who attended the emergency department (ED) with fatigue, recurrent fever, weight loss, and adenopathy for six months. Laboratory findings showed anemia, lymphocytosis, eosinophilia, thrombocytosis, cholestasis, hypoproteinemia, and hypoalbuminemia. Abdominopelvic computed tomography (CT) revealed multiple adenopathies. A lymph node biopsy yielded inconclusive results in the outpatient clinic. Later, during admission, the patient underwent a positron emission tomography-computed tomography (PET-CT), revealing a cervical adenopathy cluster that was excised en bloc. Histology confirmed the diagnosis of AITL. The medical team initiated chemotherapy but opted for exclusive symptomatic treatment due to disease progression. The patient died six months after diagnosis. The fluctuating and nonspecific presentation of AITL can hinder and delay definitive diagnosis, therefore impacting treatment and prognosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223733PMC
http://dx.doi.org/10.7759/cureus.61670DOI Listing

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