AI Article Synopsis
- Mycobacterium abscessus is a newly recognized pathogen linked to various infections, especially in patients with pre-existing respiratory issues, and is resistant to most antibiotics, making treatment challenging.
- A case study highlighted a patient whose first symptom of infection was hemoptysis (coughing up blood), diagnosed using bronchoscopy and next-generation sequencing (NGS).
- The study concluded that for patients with hemoptysis, conventional antibiotic treatment is often ineffective, suggesting that obtaining tissue samples for accurate diagnosis via bronchoscopy or lung biopsy, followed by NGS if needed, is crucial.
Article Abstract
Background: Mycobacterium abscessus is a new pathogen in recent years, which belongs to non-tuberculosis mycobacterium. Mycobacterium abscessus is widely involved in many nosocomial infections and secondary aggravation of genetic respiratory diseases. Mycobacterium abscessus is naturally resistant to most antibiotics and is difficult to treat. We report a case of mycobacterium abscessus infection with hemoptysis as the first manifestation.
Methods: Bronchoscopy, next-generation sequencing (NGS).
Results: Acid-fast staining of bronchoscopic lavage fluid showed that a small amount of acid-fast bacilli could be seen. NGS test showed the presence of Mycobacterium abscess, sequence number 137 (reference range ≥ 0), and symptomatic treatment against non-tuberculosis mycobacteria.
Conclusions: For the follow-up infection of patients with hemoptysis, the treatment effect of antibiotics is not good, so the pathological tissue should be obtained by bronchoscopy or percutaneous lung biopsy in time, and the diagnosis should be confirmed by NGS if necessary.
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Source |
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| http://dx.doi.org/10.7754/Clin.Lab.2024.240209 | DOI Listing |
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