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Article Synopsis
  • - The study investigates the differences in respiratory function and physical capacity between patients with chronic Chagas cardiomyopathy (CC) who have heart failure (HF) and those who do not.
  • - Using spirometry and a six-minute step test, the results showed that patients with HF had significantly lower lung function and functional capacity compared to those without HF.
  • - Conclusively, the research indicates that adults with CC and HF exhibit reduced lung function, suggesting a restrictive pulmonary pattern impacting their overall health.
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Article Synopsis
  • PCD (Primary Ciliary Dyskinesia) and CF (Cystic Fibrosis) are both genetic diseases that affect how the lungs work and cause issues from a young age, but PCD is thought to be milder, even though evidence is limited.
  • The study wanted to see how children with PCD compare to those with CF in terms of health over time, especially focusing on children with certain severe forms of PCD.
  • They found that kids with PCD and the severe type had lower lung function than kids with CF, but their nutrition was similar, with more CF kids getting sick from bacteria in their lungs than PCD kids.
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Objectives: Sarcoidosis is a clinically heterogenous disease. The objective of this study is the identification of clinical phenotypes using cluster analysis.

Methods: A model-based clustering relaying on 19 clinical variables was performed in a retrospective cohort of 342 sarcoidosis patients, diagnosed and followed-up from 1999 to 2019 in a tertiary hospital at Northern Spain.

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Purpose: Given the rising burden of heart failure (HF), stratification of patients at increased risk for adverse events is critical. We aimed to compare the predictive value of various maximal and submaximal cardiopulmonary exercise test (CPET) variables for adverse events in patients with HF.

Methods: A total of 237 patients with HF (66 (58-73) yr, 30% women, 70% HF with reduced ejection fraction) completed a CPET and had 5 yr of follow-up.

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