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Optimizing vancomycin therapeutic drug monitoring compliance in pediatric oncology: towards personalized medication management. | LitMetric

AI Article Synopsis

  • Vancomycin is essential for treating Gram-positive infections but requires careful monitoring to avoid treatment failures.
  • A study of 485 patients at the Children's Cancer Hospital Egypt revealed that only 54% had TDM requests for their vancomycin doses.
  • While compliance with TDM guidelines was high at 91.7%, follow-up level monitoring revealed a lower compliance rate of 66.7%, highlighting the need for better adherence in this area.

Article Abstract

Vancomycin, a crucial treatment for Gram-positive bacteria, necessitates therapeutic drug monitoring (TDM) to prevent treatment failures. We investigated the healthcare professional's compliance toward TDM of vancomycin recommendations and follow-up levels. We collected data from 485 patients who received vancomycin in the Children's Cancer Hospital Egypt 57357 medical records system (Cerner) over 4 months, from January to April 2020. Our data shows that only 54% of patients had TDM requests from healthcare professionals for the total patients who received vancomycin treatment. The healthcare professionals' compliance with the recommendations was 91.7%, while the follow-up levels were 66.7%. While overall adherence to recommendations is strong, enhancing compliance with follow-up levels remains a priority for improvement.

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Source
http://dx.doi.org/10.1080/17410541.2024.2360386DOI Listing

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