Ocular TB in Western Australia.

Int J Tuberc Lung Dis

WA TB Control Program, Perth, WA, Respiratory Medicine, Royal Perth Hospital, Perth, WA, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia.

Published: July 2024

SETTINGThis was a retrospective chart review in Western Australia, Australia.OBJECTIVETo describe the diagnosis, management, and treatment outcomes of ocular TB in Western Australia (WA).DESIGNThis was a retrospective review of ocular TB cases in WA from 2007 to 2018 with a minimum 2-year follow-up upon completion of anti-TB therapy (ATT).RESULTSA total of 44 patients were referred to WA TB clinic. Ten were excluded from the analysis of treatment response; 34 met the inclusion criteria, of whom 97.1% were born overseas. No patients had symptomatic extraocular TB. Chest X-ray showed prior pulmonary TB in 11.7% of patients ( = 4). All patients were treated with three or four ATT drugs. The most common ocular TB manifestation was retinal vasculitis (23.5%). Full resolution of ocular inflammation following ATT occurred in 66.7% ( = 22), and reduced ocular inflammation requiring only topical steroid treatment was seen in 21.2% ( = 7). Treatment failure occurred in 12.1% ( = 4). Side effects were reported in 45.6% of patients, with gastrointestinal symptoms most common (27.2%).CONCLUSIONOur study is the first Australian study examining the management of ocular TB. Our study highlights the challenges in diagnosing TB ocular disease in a low-endemicity setting and the importance of the collaboration between uveitis and TB subspecialists..

Download full-text PDF

Source
http://dx.doi.org/10.5588/ijtld.23.0353DOI Listing

Publication Analysis

Top Keywords

western australia
12
ocular
8
ocular western
8
ocular inflammation
8
patients
5
australia settingthis
4
settingthis retrospective
4
retrospective chart
4
chart review
4
review western
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!