Rock mass deformation and failure are macroscopic manifestations of crack initiation, propagation, and coalescence. However, simulating the transition of rocks from continuous to discontinuous media under cyclic dynamic loading remains challenging. This study proposes a hybrid finite-discrete element method (HFDEM) to model crack propagation, incorporating a frequency-dependent cohesive-zone model. The mechanical properties of standard sandy mudstone under quasi-static and cyclic dynamic loading were simulated using HFDEM, and the method's reliability was verified through experimental comparison. The comparative analysis demonstrates that HFDEM successfully captures crack interaction mechanisms and accurately simulates the overall failure behavior of specimens. Additionally, the effects of pre-existing flaw inclination angle and dynamic loading frequency on rock failure mechanisms were investigated. The numerical results reveal that rock samples exhibit significantly higher compressive strength under dynamic loading compared to quasi-static loading, with compressive strength increasing with higher cyclic dynamic load frequencies. Furthermore, by analyzing the strength characteristics, crack propagation, and failure modes of the samples, insights into the failure mechanisms of rocks under different frequency loads were obtained. This study provides valuable insights into crack development and failure of rocks under seismic loads, offering guidance for engineering practices.
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http://dx.doi.org/10.1038/s41598-024-66397-z | DOI Listing |
Sci Rep
January 2025
Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
In cases of large mandibular continuity defects resulting from malignancy resection, the current standard of care involves using patient-specific/custom titanium reconstruction plates along with autogenous grafts (fibula, scapula, or iliac crest segments). However, when grafts are not feasible or desired, only the reconstruction plate is used to bridge the gap. Unfortunately, metal osteosynthesis and reconstruction plates, including titanium, exhibit adverse effects such as stress-shielding and limitations in accurate postoperative irradiation (especially with proton-beam therapy).
View Article and Find Full Text PDFObjective: To investigate the biodynamics of human-exoskeleton interactions during patient handling tasks using a subject-specific modeling approach.
Background: Exoskeleton technology holds promise for mitigating musculoskeletal disorders caused by manual handling and most alarmingly by patient handling jobs. A deeper, more unified understanding of the biomechanical effects of exoskeleton use calls for advanced subject-specific models of complex, dynamic human-exoskeleton interactions.
Biosens Bioelectron
December 2024
Guangdong Provincial Key Laboratory of New Drug Screening, Guangzhou Key Laboratory of Drug Research for Emerging Virus Prevention and Treatment, NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China. Electronic address:
MicroRNA (miRNA) imaging in living cells is paramount for comprehending its dynamic functions and profiles, offering valuable insights into miRNA-related cellular processes. However, this remains challenging due to limited transfection agents and the low abundance of miRNAs. Herein, a smart nanosystem was proposed for miRNA imaging in living cells by ingeniously integrating cyclometalated ruthenium (II) nanoparticles (RuNPs) with a catalyzed hairpin assembly (CHA) strategy.
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January 2025
State Key Laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mines, Anhui University of Science and Technology, Huainan, 232001, Anhui, China.
To investigate the dynamic compression properties and crushing features of gas-containing coal under complex geological environments, a dynamic and static combined loading test system was independently developed for conducting triaxial dynamic compression tests. The dynamic stress-strain curves under different strain rates were analyzed to study the effects of strain rate and gas pressure on the dynamic mechanical characteristics. Crushed coal samples were sieved and analyzed using a standard sieve and fractal theory.
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January 2025
School of Railway Engineering, Hunan Technical College of Railway High-Speed, Hengyang, 421002, China.
Research on the evolutionary behavior of the particle breakage processes in coarse-grained soil under the action of train load is of practical significance for subgrade construction and maintenance. However, existing studies have not addressed the prediction of particle size distribution evolution. In this paper, the MTS loading system is used to simulate the dynamic train load effect on coarse-grained soil fillers.
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