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Percutaneous pulmonary thrombectomy with aspiration catheters in patients with high-risk pulmonary embolism and absolute contraindication to systemic thrombolysis. | LitMetric

AI Article Synopsis

  • High-risk pulmonary embolism (PE) poses a high mortality rate, and while systemic thrombolysis is effective, it has significant risks; percutaneous thrombectomy might be a safer alternative for patients at risk of bleeding.
  • This study evaluated the effectiveness and safety of catheter-directed thrombectomy using aspiration catheters in patients with high-risk PE who could not undergo systemic thrombolysis.
  • Results showed that the procedure was successful in all 13 patients, leading to marked improvements in hemodynamics and respiratory function without any serious complications or deaths during hospitalization or follow-up.

Article Abstract

Background: High-risk Pulmonary Embolism (PE) mortality remains very high. Systemic thrombolysis is effective but carries significant complications and contraindications related to the hemorrhagic risk. Percutaneous thrombectomy using aspiration catheters may be an alternative in patients with a high bleeding risk.

Objective: This study aimed to evaluate the results of catheter-directed thrombectomy using aspiration dedicated catheters in patients with high-risk PE and absolute contraindication to systemic thrombolysis, with specific focus on procedural success, safety, and in-hospital outcomes.

Methods: A prospective study enrolled all consecutive patients diagnosed with high-risk pulmonary embolism and absolute contraindication to systemic thrombolysis, who underwent percutaneous pulmonary thrombectomy using dedicated aspiration catheters. The study documented the effectiveness and complications of the procedure, as well as patient outcomes at discharge and during the follow-up period.

Results: Thirteen patients underwent percutaneous pulmonary thrombectomy using aspiration dedicated catheters. The procedure was successful for all patients, resulting in hemodynamic and respiratory improvement within the first 24 h. No deaths attributable to cardiovascular or respiratory causes occurred during admission or follow-up. Furthermore, no serious adverse events or complications were reported during the procedure or hospitalization.

Conclusions: Percutaneous pulmonary thrombectomy with dedicated aspiration catheters in patients with high-risk pulmonary embolism and contraindications to systemic thrombolysis was associated with excellent clinical results and low rate of complications.

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Source
http://dx.doi.org/10.1016/j.carrev.2024.06.020DOI Listing

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