AI Article Synopsis
- A 67-year-old Japanese woman with liver cirrhosis from primary biliary cholangitis was admitted to the hospital after losing consciousness.
- She was diagnosed with hepatic encephalopathy (HE) through imaging and symptoms assessment.
- Molecular tests showed a link between urease-positive S. salivarius found in her saliva and stool, suggesting it may contribute to increased ammonia production and subsequent HE in cirrhosis patients.
Article Abstract
We herein report a 67-year-old Japanese woman with liver cirrhosis caused by primary biliary cholangitis. The patient was admitted to the hospital with loss of consciousness. Hepatic encephalopathy (HE) was diagnosed after diagnostic imaging and symptom assessments. Molecular biology tests were performed on oral saliva and stool samples. The test results indicated sequence similarity between urease-positive S. salivarius in both oral saliva and stool, as revealed by the signals in the overlapping peaks. This bacterium can potentially increase ammonia production in the gut, leading to HE in patients with liver cirrhosis.
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| http://dx.doi.org/10.2169/internalmedicine.3989-24 | DOI Listing |
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