Porokeratosis on the lip: A Case Series.

Dermatol Online J

School of Medicine, University of Nevada Reno, Reno, Nevada, USA Skin Cancer and Dermatology Institute, Reno, Nevada, USA.

Published: April 2024

AI Article Synopsis

  • Porokeratosis is a skin condition marked by the development of benign plaques, featuring a distinctive raised ridge and a flat center, which can lead to squamous cell carcinoma if untreated.
  • The condition is mostly found on extremities, with rare occurrences on the lip, as highlighted by the report of three cases involving lip lesions.
  • Treatment options included cryotherapy, which failed in two patients, while one patient was successfully treated with a shave biopsy, and another was lost to follow-up.

Article Abstract

Porokeratosis is a skin condition that involves the formation of plaques, characterized by a hyperkeratotic ridge with an atrophic center. There is a histological presence of a cornoid lamella, which is a parakeratotic column that traverses through the stratum corneum. The plaques are mostly benign but have the potential to become squamous cell carcinomas if left untreated. Porokeratosis lesions typically occur on the extremities, but they can develop anywhere. The occurrence of porokeratosis on the lip is exceedingly rare. We report three cases of porokeratosis on the lip. Each incidence was treated with cryotherapy, which was unsuccessful in two. One of these two patients did not elect for topical treatment and is being monitored for lesion changes. The second patient was successfully treated via shave biopsy. The third patient was lost to follow-up post-cryotherapy.

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Source
http://dx.doi.org/10.5070/D330263592DOI Listing

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