Fit for purpose: Selecting the best mitochondrial DNA for the job.

Cell Metab

Mitochondrial Research Group, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK. Electronic address:

Published: July 2024

The factors determining levels of pathogenic mitochondrial DNA in cells and tissues are critical to disease pathology but remain poorly understood and contentious. In Nature, Kotrys et al. published a single-cell-based analysis casting fresh light on this thorny problem and introduced a powerful new investigative tool.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2024.06.011DOI Listing

Publication Analysis

Top Keywords

mitochondrial dna
8
fit purpose
4
purpose selecting
4
selecting best
4
best mitochondrial
4
dna job
4
job factors
4
factors determining
4
determining levels
4
levels pathogenic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!