Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism.

Case Rep Psychiatry

Department of Psychiatry Lehigh Valley Health Network, Bethlehem, Pennsylvania, USA.

Published: June 2024

AI Article Synopsis

  • A 28-year-old male with a history of cannabis use experienced psychotic symptoms like mood swings and odd behavior, leading to his first psychiatric evaluation.
  • After diagnosing him with hypercalcemia, tests confirmed primary hyperparathyroidism (PHPT) as the underlying cause.
  • Following surgery to remove the parathyroid gland, the patient no longer required psychiatric medications, highlighting the need to explore organic causes of psychosis, especially in individuals with substance use issues.

Article Abstract

Primary hyperparathyroidism (PHPT) and subsequent hypercalcemia have been reported to be associated with psychosis. Here we report the case of a 28-year-old cannabis using male with his first contact with psychiatric care because of mood instability, bizarre behavior, and poor ability to carry out activities of daily living. Hypercalcemia was identified, and a subsequent endocrine workup confirmed PHPT. After parathyroidectomy, there was no longer any need for antipsychotic or other psychotropic medications; the report emphasizes the importance of considering organic causes, such as hyperparathyroidism, in patients presenting with psychotic-like symptoms, including in the setting of substance use disorder. Prompt recognition and appropriate management of the underlying condition are crucial for optimizing patient outcomes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217570PMC
http://dx.doi.org/10.1155/2024/8126125DOI Listing

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