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Differential Biological Effects of Extracts-In Vitro Studies on Breast Cancer Models.
Antioxidants (Basel)
November 2024
Cell Biology Laboratory, "Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.
The increasing popularity of herbal supplements emphasizes the need of scientific data regarding their health benefits and possible toxicological concerns. The complexity of botanical extracts, which include thousands of distinct compounds, contributes to the challenging nature of this endeavor. In this study, we explored the hormetic effects of two extracts on breast cell lines.
View Article and Find Full Text PDFProspective study of peripartum group B streptococcus colonization in Japanese mothers and neonates.
Epidemiol Infect
January 2025
Department of Obstetrics and Gynecology, Juntendo University Urayasu Hospital, Chiba, Japan.
Article Synopsis
- Group B streptococcus (GBS) is a significant cause of infections in neonates and pregnant women, with Japan implementing guidelines for screening and antibiotic use, yet infections have not decreased significantly.
- Approximately 15% of pregnant women lack GBS screening, and issues like intermittent colonization lead to early-onset disease; current preventative measures don't address increasing cases of late-onset disease.
- This study found that using polymerase chain reaction for GBS detection was more effective than culture methods, highlighted the risk of horizontal transmission, and emphasized the need for better diagnostic tools and potential maternal vaccination for prevention.
Bioactive peptides with potential anticancer properties from various food protein sources: status of recent research, production technologies, and developments.
Crit Rev Biotechnol
January 2025
Food Science Department, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al-Ain, United Arab Emirates.
Recently, bioactive peptides, from natural resources, have attracted remarkable attention as nutraceutical treasures and the health benefits of their consumption have extensively been studied. Therapies based on bioactive peptides have been recognized as an innovative and promising alternative method for dangerous diseases such as cancer. Indeed, there has been enormous interest in nutraceuticals and bioactive-based chemopreventive molecules as a potential opportunity to manage chronic diseases, including cancer at different stages, rather than the traditionally used therapies.
View Article and Find Full Text PDFSelective outcome reporting concerning antibiotics and third molar surgery.
Clin Oral Investig
January 2025
Department of Oral and Maxillofacial Surgery, School of Dentistry, University of São Paulo, Av. Prof. Lineu Prestes, 2227 - Cidade Universitária, São Paulo, 05508-000, Brazil.
Objectives: This study evaluates the selective outcome reporting (SOR) in clinical trials on antibiotic use in third molar surgeries. It explores how SOR may bias results and affect systematic reviews, potentially leading to misinterpretations of intervention efficacy.
Materials And Methods: A search was conducted on "ClinicalTrials.
Chemoprevention of natural product against oral cancer: A comprehensive review.
Malays J Pathol
December 2024
Universiti Sains Malaysia, School of Dental Sciences, Health Campus, Kubang Kerian, Kelantan, Malaysia.
Introduction: Oral cancer is considered the sixth most common form of cancer worldwide. It causes significant morbidity and mortality, especially in low socioeconomic status groups. However, Cancer chemoprevention encompasses the use of specific compounds to suppress the growth of tumours or inhibit carcinogenesis.
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