AI Article Synopsis
- A young woman with clozapine-resistant schizoaffective disorder struggled with persistent auditory hallucinations despite various treatments, including electroconvulsive therapy and multiple antipsychotics.
- She suffered a haemorrhagic stroke caused by a ruptured arteriovenous malformation in the right superior temporal gyrus, which was surgically removed.
- Following the stroke, although she had some neurological deficits, her auditory hallucinations ceased, suggesting that personalized neuromodulation could be a more effective treatment for similar conditions in the future.
Article Abstract
We present a young woman with clozapine-resistant schizoaffective disorder who was treated with maintenance electroconvulsive therapy and multiple antipsychotics but continued to have auditory hallucinations. She had a haemorrhagic stroke secondary to a ruptured arteriovenous malformation at the right superior temporal gyrus, which was excised during emergency craniotomy. Despite having neurological deficits after the stroke, she reported cessation of auditory hallucinations. Magnetic resonance imaging of the brain showed Wallerian degeneration over the right temporal region. Personalised neuromodulation intervention may be a more effective treatment option for clozapine-resistant schizophrenia.
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| http://dx.doi.org/10.12809/eaap2340 | DOI Listing |
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