Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4088/PCC.23cr03696 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Single oral dose of gabapentin reduces vigilance and increases play behavior without changing mobility in New Zealand white rabbits (Oryctolagus cuniculus).
J Am Vet Med Assoc
December 2024
4Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO.
Objective: To evaluate rabbit behavioral responses and activity after gabapentin administration.
Methods: In this study, 5 intact female and 3 intact male New Zealand white rabbits aged 8 to 12 months were administered a single oral 25-mg/kg dose of gabapentin. This study was conducted from December 2020 to February 2021.
Potassium Nitrate in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial.
JAMA Cardiol
December 2024
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: Nitric oxide deficiency may contribute to exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF). Prior pilot studies have shown improvements in exercise tolerance with single-dose and short-term inorganic nitrate administration.
Objective: To assess the impact of chronic inorganic nitrate administration on exercise tolerance in a larger trial of participants with HFpEF.
Pivmecillinam for Uncomplicated Acute Cystitis: A Contemporary Review.
Ann Pharmacother
December 2024
Department of Pharmacy Practice, ETSU Bill Gatton College of Pharmacy, East Tennessee State University, Johnson City, TN, USA.
Article Synopsis
- - The review highlights the efficacy and safety of pivmecillinam in treating uncomplicated acute cystitis, based on data from six randomized controlled trials showing effectiveness at doses of 200 to 400 mg taken three times daily for 3 to 7 days.
- - Higher doses (400 mg) and longer treatment durations resulted in better clinical and bacteriologic outcomes, while pivmecillinam is particularly beneficial for populations not commonly approved by the FDA, like men or pregnant women.
- - As antibiotic resistance increases, pivmecillinam offers a new, potentially effective outpatient treatment option for uncomplicated acute cystitis in the U.S., with a focus on cost and its low resistance profile in managing uropathogens. *
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!