AI Article Synopsis
- Diagnosing low-grade adenosquamous carcinoma (LGASC) is challenging due to its subtle appearance and similarity to benign conditions, making identification difficult.
- A 53-year-old woman initially diagnosed with a benign growth underwent a wider excision, which unexpectedly revealed LGASC with some expression of estrogen receptors.
- The case underscores the diagnostic difficulties associated with LGASC, particularly when relying on small tissue samples from biopsies.
Article Abstract
Introduction: Diagnosing low-grade adenosquamous carcinoma (LGASC) presents significant challenges due to its subtle morphology, variable immunohistochemical expression, and resemblance to benign lesions like radial scar and complex sclerosing lesions.
Case Presentation: We present a case of a 53-year-old woman with a subareolar mass initially thought to be a fibroepithelial neoplasm on core biopsy. Subsequent wide excision revealed LGASC with oestrogen receptor expression (weak to moderate intensity, 40% of tumour cells).
Conclusion: These findings, rarely reported, highlight the difficulty of diagnosing LGASC on small tissue samples.
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| http://dx.doi.org/10.1159/000540029 | DOI Listing |
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