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Automated detection of traumatic bleeding in CT images using 3D U-Net# and multi-organ segmentation.
Biomed Phys Eng Express
January 2025
Chiba University Center for Frontier Medical Engineering, 1-33 Yayoi-cho, Inage-ku, Chiba, Chiba, 263-8522, JAPAN.
Traumatic injury remains a leading cause of death worldwide, with traumatic bleeding being one of its most critical and fatal consequences. The use of whole-body computed tomography (WBCT) in trauma management has rapidly expanded. However, interpreting WBCT images within the limited time available before treatment is particularly challenging for acute care physicians.
View Article and Find Full Text PDFEfficient Generative-Adversarial U-Net for Multi-Organ Medical Image Segmentation.
J Imaging
January 2025
School of Computer Science and Artificial Intelligence, Changzhou University, Changzhou 213000, China.
Manual labeling of lesions in medical image analysis presents a significant challenge due to its labor-intensive and inefficient nature, which ultimately strains essential medical resources and impedes the advancement of computer-aided diagnosis. This paper introduces a novel medical image-segmentation framework named Efficient Generative-Adversarial U-Net (EGAUNet), designed to facilitate rapid and accurate multi-organ labeling. To enhance the model's capability to comprehend spatial information, we propose the Global Spatial-Channel Attention Mechanism (GSCA).
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Curr Res Toxicol
December 2024
University of Central Florida, NanoScience Technology Center, 12424 Research Parkway, Suite 400, Orlando, FL 23826, United States.
Opioids have been the primary method used to manage pain for hundreds of years, however the increasing prescription rate of these drugs in the modern world has led to a public health crisis of overdose related deaths. Naloxone is the current standard treatment for opioid overdose rescue, but it has not been fully investigated for potential off-target toxicity effects. The current methods for pharmaceutical development do not correlate well with pre-clinical animal studies compared to clinical results, creating a need for improved methods for therapeutic evaluation.
View Article and Find Full Text PDFContinuous Core Body Temperature Monitoring for Heatstroke Alert via a Wearable In-Ear Thermometer.
ACS Sens
January 2025
Department of Emergency, Shanghai Changhai Hospital, Shanghai 200433, China.
Heatstroke, a global concern exacerbated by climate change, poses significant health risks, potentially leading to multiorgan damage and fatalities. Core body temperature (CBT) is a critical and precise indicator of heatstroke, and its continuous monitoring could serve as a pivotal tool for early detection. Traditional CBT measurements, often invasive (e.
View Article and Find Full Text PDFUnlocking the potential of CRISPR-Cas9 for cystic fibrosis: A systematic literature review.
Gene
January 2025
Department of Biomedical Engineering, Gallogly College of Engineering, University of Oklahoma Norman OK USA.
CRISPR-Cas9 technology has revolutionized genetic engineering, offering precise and efficient genome editing capabilities. This review explores the application of CRISPR-Cas9 for cystic fibrosis (CF), particularly targeting mutations in the CFTR gene. CF is a multiorgan disease primarily affecting the lungs, gastrointestinal system (e.
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